C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MDM2 binding protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172167 MTBP 9606 + 8:120445400-120542133 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000305949 MTBP-001 120445426-120523635 protein_coding
  ENST00000456899 MTBP-005 120445400-120451335 retained_intron
  ENST00000519188 MTBP-006 120488161-120490703 retained_intron
  ENST00000519556 MTBP-007 120518703-120541965 nonsense_mediated_decay
  ENST00000519841 MTBP-008 120538695-120542133 processed_transcript
  ENST00000522308 MTBP-002 120445422-120452829 retained_intron
  ENST00000522449 MTBP-004 120459276-120473950 retained_intron
  ENST00000523373 MTBP-003 120445422-120470937 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastOvaryPlacentaTestisENST00000305949
Transcript ID Breast Ovary Placenta Testis
ENST00000305949 1.554±0.00 2.391±1.13 0.805±0.00 2.540±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00009J CIL_00009J_0002 CGP 8:120059780-120445402
CIL_00008U CIL_00008U_0002 CGP 8:120380761-120542133
CIL_0002GD CIL_0002GD_0002 CGP 8:120445400-120813273

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000776 IDA kinetochore
GO:0000785 IDA chromatin
GO:0005515 IEA protein binding
GO:0007050 IEA cell cycle arrest
GO:0007089 IEA traversing start control point of mitotic cell cycle
GO:0008285 IEA negative regulation of cell proliferation
GO:0034501 IMP protein localization to kinetochore
GO:0045839 IEA negative regulation of mitosis
GO:0071174 IGI mitotic spindle checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090447 MTBP MDM2 binding protein protein_coding Danio_rerio
ENSMUSG00000022369 Mtbp Mdm2, transformed 3T3 cell double minute p53 binding protein protein_coding Mus_musculus

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