C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Mdm2, transformed 3T3 cell double minute p53 binding protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022369 Mtbp 10090 + 15:55557408-55626423 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022998 Mtbp-001 55557408-55626423 protein_coding
  ENSMUST00000166449 Mtbp-006 55621452-55626421 processed_transcript
  ENSMUST00000169517 Mtbp-004 55557735-55569077 nonsense_mediated_decay
  ENSMUST00000169667 Mtbp-003 55576780-55626422 protein_coding
  ENSMUST00000170046 Mtbp-002 55557595-55610813 protein_coding
  ENSMUST00000171146 Mtbp-005 55617587-55619938 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENSMUST00000022998ENSMUST00000170046ENSMUST00000171146
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000022998 0.643±0.01 0.435±0.14 1.941±0.25 3.217±0.94 0.828±0.34 0.701±0.26 1.087±0.13 7.714±3.10 1.395±0.00 1.923±1.26 3.518±1.75 4.449±1.33
ENSMUST00000170046 1.252±0.00 0.274±0.00 N/A N/A 0.469±0.00 0.620±0.12 N/A N/A N/A 0.751±0.32 N/A 3.136±0.24
ENSMUST00000171146 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 48.786±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00009J CIL_00009J_0003 CGP 15:55307750-55557748
CIL_00008U CIL_00008U_0003 CGP 15:55534094-55626423
CIL_0002GD CIL_0002GD_0003 CGP 15:55557408-55906949

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000776 IDA kinetochore
GO:0000785 IEA chromatin
GO:0005515 IPI protein binding
GO:0007050 IEA cell cycle arrest
GO:0007089 IDA traversing start control point of mitotic cell cycle
GO:0008285 IDA negative regulation of cell proliferation
GO:0034501 IEA protein localization to kinetochore
GO:0045839 IDA negative regulation of mitosis
GO:0071174 IEA mitotic spindle checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090447 MTBP MDM2 binding protein protein_coding Danio_rerio
ENSG00000172167 MTBP MDM2 binding protein protein_coding Homo_sapiens

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