C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000173692 PSMD1 9606 + 2:231056864-231172827 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000308696 PSMD1-001 231056864-231172827 protein_coding
  ENST00000373635 PSMD1-201 231056864-231172824 protein_coding
  ENST00000409643 PSMD1-003 231056894-231170712 protein_coding
  ENST00000431051 PSMD1-002 231056867-231165235 nonsense_mediated_decay
  ENST00000440838 PSMD1-005 231056875-231070106 protein_coding
  ENST00000444007 PSMD1-006 231066904-231075566 protein_coding
  ENST00000447633 PSMD1-009 231083564-231139070 protein_coding
  ENST00000467792 PSMD1-010 231153469-231163710 retained_intron
  ENST00000477120 PSMD1-011 231163093-231165287 retained_intron
  ENST00000481003 PSMD1-012 231164959-231165894 retained_intron
  ENST00000488354 PSMD1-007 231085080-231109122 processed_transcript
  ENST00000491229 PSMD1-008 231170402-231172760 retained_intron
  ENST00000619128 PSMD1-202 231060356-231172824 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000308696ENST00000373635ENST00000409643ENST00000431051ENST00000619128
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000308696 14.621±0.00 12.176±0.00 1.722±0.00 9.002±4.57 11.799±4.74 9.949±2.51 7.612±4.54 7.505±1.98 7.758±1.09 6.209±1.22 11.154±1.33 17.781±10.32 14.000±0.36 13.860±0.00
ENST00000373635 N/A N/A N/A N/A N/A 6.914±0.00 N/A 6.521±0.00 N/A N/A N/A N/A N/A 6.013±0.00
ENST00000409643 7.545±0.00 4.609±0.00 N/A 25.231±0.00 6.634±0.00 N/A 4.937±0.00 6.849±0.00 N/A 2.810±1.03 6.172±0.00 10.928±0.00 13.336±0.00 7.258±0.28
ENST00000431051 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.443±0.00 N/A 5.014±0.00
ENST00000619128 N/A N/A N/A 5.302±0.00 5.848±0.00 N/A 1.495±0.00 N/A 4.230±0.00 3.290±0.00 N/A 7.496±2.57 10.887±4.56 5.128±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00076M CIL_00076M_0001 CGP 2:231037490-231172827
CIL_0004KX CIL_0004KX_0002 CGP 2:231056864-231172827

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 IDA:IEA proteasome complex
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005488 IEA binding
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0005838 TAS proteasome regulatory particle
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0022624 ISS proteasome accessory complex
GO:0030234 IEA enzyme regulator activity
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042176 IEA regulation of protein catabolic process
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003189 psmd1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 protein_coding Danio_rerio
ENSMUSG00000026229 Psmd1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 protein_coding Mus_musculus
ENSMUSG00000094638 Gm21972 predicted gene 21972 protein_coding Mus_musculus

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