C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: C-terminal binding protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000175029 CTBP2 9606 - 10:124984317-125161170 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000309035 CTBP2-006 124988938-125027890 protein_coding
  ENST00000334808 CTBP2-005 124989135-125006013 protein_coding
  ENST00000337195 CTBP2-001 124984317-125160513 protein_coding
  ENST00000395705 CTBP2-015 124993267-125003000 nonsense_mediated_decay
  ENST00000411419 CTBP2-011 124989225-125161026 protein_coding
  ENST00000460976 CTBP2-004 125003338-125160145 processed_transcript
  ENST00000467395 CTBP2-008 125110997-125159957 processed_transcript
  ENST00000476817 CTBP2-010 125038997-125161170 processed_transcript
  ENST00000486955 CTBP2-012 124997792-125003384 retained_intron
  ENST00000493552 CTBP2-009 125003464-125028028 processed_transcript
  ENST00000494626 CTBP2-002 124989225-125160499 protein_coding
  ENST00000530884 CTBP2-014 125039046-125161061 protein_coding
  ENST00000530930 CTBP2-013 125100587-125138250 processed_transcript
  ENST00000531469 CTBP2-003 124989225-125158716 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaENST00000309035ENST00000334808ENST00000337195ENST00000494626ENST00000531469
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta
ENST00000309035 N/A N/A N/A N/A N/A N/A N/A N/A N/A 28.131±0.00 N/A
ENST00000334808 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.191±0.00
ENST00000337195 4.265±0.00 N/A 6.043±0.00 4.941±0.00 6.257±4.06 0.615±0.00 6.579±0.00 0.942±0.10 11.533±0.00 6.073±3.81 5.547±1.37
ENST00000494626 N/A N/A N/A N/A N/A N/A N/A N/A N/A 19.277±0.00 N/A
ENST00000531469 N/A 4.063±0.00 N/A 7.057±0.00 5.903±0.00 N/A N/A N/A N/A 25.810±13.40 8.541±2.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00084V CIL_00084V_0001 VISTA 10:124437964-125038882
CIL_0001V2 CIL_0001V2_0001 CGP 10:124801785-124988189
CIL_0009BC CIL_0009BC_0001 VISTA 10:124916753-125517434
CIL_0003UU CIL_0003UU_0001 CGP 10:124942123-125161170
CIL_0001V4 CIL_0001V4_0001 CGP 10:124984317-125683144

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003682 IEA chromatin binding
GO:0003713 IEA transcription coactivator activity
GO:0003714 IEA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0008152 IEA metabolic process
GO:0008285 TAS negative regulation of cell proliferation
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0017053 ISS transcriptional repressor complex
GO:0019079 TAS viral genome replication
GO:0030054 IEA cell junction
GO:0035563 IEA positive regulation of chromatin binding
GO:0042974 IEA retinoic acid receptor binding
GO:0045202 IEA synapse
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048386 IEA positive regulation of retinoic acid receptor signaling pathway
GO:0050872 ISS white fat cell differentiation
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075712 CTBP2 C-terminal binding protein 2 protein_coding Danio_rerio
ENSMUSG00000030970 Ctbp2 C-terminal binding protein 2 protein_coding Mus_musculus

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