C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mediator complex subunit 16
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000175221 MED16 9606 - 19:867630-893218 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000269814 MED16-201 867964-893200 protein_coding
  ENST00000312090 MED16-003 867853-893193 protein_coding
  ENST00000325464 MED16-202 867964-893218 protein_coding
  ENST00000395808 MED16-001 867630-893218 protein_coding
  ENST00000586017 MED16-011 873536-891148 protein_coding
  ENST00000586342 MED16-004 890984-892815 protein_coding
  ENST00000589119 MED16-006 867963-891131 protein_coding
  ENST00000592373 MED16-020 885822-893158 nonsense_mediated_decay
  ENST00000592943 MED16-005 873536-891148 protein_coding
  ENST00000606248 MED16-023 867964-893216 nonsense_mediated_decay
  ENST00000606828 MED16-002 873536-891148 protein_coding
  ENST00000607471 MED16-021 867963-885909 protein_coding
  ENST00000616387 MED16-203 867972-891148 protein_coding
  ENST00000617672 MED16-204 867972-891148 protein_coding
  ENST00000621073 MED16-039 867963-871066 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000269814ENST00000312090ENST00000325464ENST00000395808ENST00000586017ENST00000589119ENST00000592373ENST00000592943ENST00000606248ENST00000607471
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000269814 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.676±0.00 N/A N/A N/A N/A
ENST00000312090 3.245±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 2.179±0.00 N/A 8.468±0.00 N/A N/A
ENST00000325464 N/A 8.912±0.00 1.047±0.00 0.947±0.00 N/A N/A N/A 7.016±3.61 2.514±1.32 N/A 4.676±1.46 10.443±10.15 9.209±3.42 12.082±5.42
ENST00000395808 9.510±0.00 N/A N/A 1.796±0.00 13.164±0.00 N/A 2.538±0.00 N/A N/A 1.239±0.72 N/A 11.834±5.93 N/A N/A
ENST00000586017 N/A N/A N/A 0.909±0.00 2.159±0.00 2.439±0.00 N/A N/A N/A N/A 1.817±0.00 1.131±0.00 N/A N/A
ENST00000589119 N/A N/A 0.467±0.00 4.540±0.00 N/A 3.688±0.00 2.663±0.00 6.942±0.00 4.528±0.00 6.591±0.00 12.967±0.00 13.813±0.00 16.037±3.57 N/A
ENST00000592373 N/A N/A N/A N/A 0.991±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000592943 N/A N/A N/A 1.228±0.00 1.042±0.00 N/A 0.467±0.00 N/A N/A 1.082±0.00 1.387±0.00 N/A N/A N/A
ENST00000606248 N/A 4.073±0.00 N/A 2.244±0.00 N/A 5.262±0.00 0.266±0.00 N/A N/A N/A N/A 6.364±0.00 N/A N/A
ENST00000607471 N/A 8.561±0.00 N/A 2.164±1.41 N/A 2.084±1.67 0.226±0.00 5.346±0.00 4.284±0.00 2.142±1.69 10.331±0.00 20.934±0.00 20.108±9.30 20.670±7.45

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XG CIL_0008XG_0001 VISTA 19:477571-1083531
CIL_0000HX CIL_0000HX_0001 CGP 19:859643-893218
CIL_00011Z CIL_00011Z_0001 CGP 19:867630-913245

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003712 IDA transcription cofactor activity
GO:0003713 TAS transcription coactivator activity
GO:0003824 IEA catalytic activity
GO:0004872 IDA receptor activity
GO:0005515 IEA protein binding
GO:0005634 NAS nucleus
GO:0005654 TAS nucleoplasm
GO:0006357 NAS regulation of transcription from RNA polymerase II promoter
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006367 IDA transcription initiation from RNA polymerase II promoter
GO:0008152 IEA metabolic process
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016592 IDA mediator complex
GO:0030375 IDA thyroid hormone receptor coactivator activity
GO:0030518 IDA intracellular steroid hormone receptor signaling pathway
GO:0030521 IDA androgen receptor signaling pathway
GO:0042809 NAS vitamin D receptor binding
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046966 IDA thyroid hormone receptor binding
GO:2000273 IDA positive regulation of receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040779 med16 mediator complex subunit 16 protein_coding Danio_rerio
ENSMUSG00000013833 Med16 mediator complex subunit 16 protein_coding Mus_musculus

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