C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: iroquois homeobox 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000176842 IRX5 9606 + 16:54930862-54934485 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000320990 IRX5-002 54931199-54934485 protein_coding
  ENST00000394636 IRX5-001 54930862-54934485 protein_coding
  ENST00000558597 IRX5-004 54932072-54934069 protein_coding
  ENST00000560154 IRX5-003 54931199-54933960 protein_coding
  ENST00000620085 IRX5-201 54931199-54933960 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000320990ENST00000394636ENST00000558597ENST00000560154ENST00000620085
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000320990 N/A 0.122±0.00 N/A N/A 0.743±0.00 N/A N/A 0.261±0.00 N/A N/A 0.173±0.00 N/A 0.263±0.00
ENST00000394636 0.441±0.00 0.186±0.00 0.612±0.00 0.053±0.00 0.448±0.01 1.679±0.13 1.499±0.00 N/A 0.779±0.00 0.808±0.46 0.201±0.00 N/A N/A
ENST00000558597 N/A N/A N/A N/A 1.273±0.00 1.091±0.00 0.836±0.00 N/A 0.744±0.00 1.170±0.00 0.836±0.91 0.218±0.17 2.687±0.00
ENST00000560154 N/A N/A N/A N/A 1.996±0.00 3.642±0.00 1.503±0.86 N/A N/A N/A 0.207±0.00 N/A N/A
ENST00000620085 N/A N/A N/A N/A N/A N/A N/A N/A 2.711±0.00 N/A 0.270±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ON CIL_0007ON_0002 UCNEbase 16:51906374-55391377
CIL_0006IA CIL_0006IA_0001 CGP 16:54283304-54934485
CIL_0008ZG CIL_0008ZG_0001 VISTA 16:54331417-54933346
CIL_0008ZF CIL_0008ZF_0001 VISTA 16:54345555-54946447
CIL_0008ZB CIL_0008ZB_0001 VISTA 16:54450731-55051703
CIL_0008ZC CIL_0008ZC_0001 VISTA 16:54465190-55066248
CIL_000986 CIL_000986_0001 VISTA 16:54740448-55341163
CIL_000989 CIL_000989_0001 VISTA 16:54745325-55346517
CIL_00098A CIL_00098A_0001 VISTA 16:54889273-55490371
CIL_000987 CIL_000987_0001 VISTA 16:54906681-55507962
CIL_0006KT CIL_0006KT_0001 CGP 16:54930862-55330760

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002027 IEA regulation of heart rate
GO:0003677 IEA DNA binding
GO:0005499 IEA vitamin D binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007601 IEA visual perception
GO:0008406 IMP gonad development
GO:0010468 IEA regulation of gene expression
GO:0042551 IEA neuron maturation
GO:0043565 IEA sequence-specific DNA binding
GO:0048468 IEA cell development
GO:0048701 IMP embryonic cranial skeleton morphogenesis
GO:0050896 IEA response to stimulus
GO:0060040 IEA retinal bipolar neuron differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034043 irx5a iroquois homeobox protein 5a protein_coding Danio_rerio
ENSDARG00000074070 irx5b iroquois homeobox protein 5b protein_coding Danio_rerio
ENSMUSG00000031737 Irx5 Iroquois related homeobox 5 (Drosophila) protein_coding Mus_musculus

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