C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: iroquois homeobox 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000177508 IRX3 9606 - 16:54283304-54286763 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000329734 IRX3-001 54283304-54286763 protein_coding
  ENST00000558054 IRX3-003 54283436-54285855 protein_coding
  ENST00000558180 IRX3-002 54284120-54286724 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000329734ENST00000558054ENST00000558180
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000329734 0.633±0.00 6.251±0.00 0.132±0.00 1.748±1.66 0.162±0.00 6.725±6.18 3.808±3.55 0.177±0.06 4.680±1.90 2.463±0.00 0.964±0.75 0.778±0.18 0.886±0.80
ENST00000558054 N/A N/A N/A N/A N/A N/A 0.207±0.00 0.631±0.00 N/A 0.692±0.00 N/A N/A N/A
ENST00000558180 N/A N/A 0.075±0.00 3.018±2.41 0.741±0.00 0.551±0.00 N/A N/A N/A 2.008±0.00 1.055±0.71 N/A 0.562±0.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ON CIL_0007ON_0002 UCNEbase 16:51906374-55391377
CIL_0000UO CIL_0000UO_0001 CGP 16:53703963-54286763
CIL_0007S8 CIL_0007S8_0001 VISTA 16:53758702-54360209
CIL_000856 CIL_000856_0001 VISTA 16:53798739-54400045
CIL_0007S7 CIL_0007S7_0001 VISTA 16:53805894-54406356
CIL_0007S6 CIL_0007S6_0001 VISTA 16:53809942-54410955
CIL_000857 CIL_000857_0001 VISTA 16:53915682-54517241
CIL_0007S5 CIL_0007S5_0001 VISTA 16:53989508-54590424
CIL_0007S4 CIL_0007S4_0001 VISTA 16:54016433-54617773
CIL_00080I CIL_00080I_0001 VISTA 16:54051107-54651727
CIL_00080Q CIL_00080Q_0001 VISTA 16:54189263-54790155
CIL_00080P CIL_00080P_0001 VISTA 16:54206390-54807534
CIL_00080L CIL_00080L_0001 VISTA 16:54241966-54844013
CIL_00080M CIL_00080M_0001 VISTA 16:54245814-54846743
CIL_00080N CIL_00080N_0001 VISTA 16:54277555-54878525
CIL_00080R CIL_00080R_0001 VISTA 16:54282300-54883125
CIL_0006IA CIL_0006IA_0001 CGP 16:54283304-54934485

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001656 IEA metanephros development
GO:0003677 IEA DNA binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007498 IEA mesoderm development
GO:0030424 IEA axon
GO:0043565 IEA sequence-specific DNA binding
GO:0045665 IEA negative regulation of neuron differentiation
GO:0045666 IEA positive regulation of neuron differentiation
GO:0072047 IEA proximal/distal pattern formation involved in nephron development
GO:0072086 IEA specification of loop of Henle identity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031138 irx3b iroquois homeobox protein 3b protein_coding Danio_rerio
ENSDARG00000052947 irx3a iroquois homeobox protein 3a protein_coding Danio_rerio
ENSMUSG00000031734 Irx3 Iroquois related homeobox 3 protein_coding Mus_musculus

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