C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Iroquois related homeobox 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031734 Irx3 10090 - 8:91798525-91801916 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000093312 Irx3-002 91798525-91801915 protein_coding
  ENSMUST00000175795 Irx3-001 91798525-91801916 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000093312ENSMUST00000175795
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000093312 N/A N/A 0.248±0.00 N/A 0.072±0.00 0.037±0.02 N/A N/A 0.049±0.02 N/A 0.804±0.00 3.181±0.00 N/A 0.023±0.00
ENSMUST00000175795 1.325±0.84 8.292±1.53 0.237±0.00 7.284±4.65 6.159±3.26 0.048±0.03 6.080±2.49 13.075±2.07 0.057±0.03 31.280±3.66 1.219±0.30 12.258±3.86 18.088±10.70 0.085±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ON CIL_0007ON_0003 UCNEbase 8:88447800-92743752
CIL_0007X2 CIL_0007X2_0002 VISTA 8:91208767-91810326
CIL_0007X0 CIL_0007X0_0002 VISTA 8:91238298-91839821
CIL_0007WZ CIL_0007WZ_0002 VISTA 8:91245726-91847572
CIL_0000UO CIL_0000UO_0002 CGP 8:91313532-91801916
CIL_0007S8 CIL_0007S8_0002 VISTA 8:91322042-91923486
CIL_000856 CIL_000856_0002 VISTA 8:91356701-91958041
CIL_0007S7 CIL_0007S7_0002 VISTA 8:91361914-91962349
CIL_0007S6 CIL_0007S6_0002 VISTA 8:91364604-91965497
CIL_000857 CIL_000857_0002 VISTA 8:91449887-92051412
CIL_0007S5 CIL_0007S5_0002 VISTA 8:91504616-92105515
CIL_0007S4 CIL_0007S4_0002 VISTA 8:91526762-92128112
CIL_00080I CIL_00080I_0002 VISTA 8:91555876-92156486
CIL_00080Q CIL_00080Q_0002 VISTA 8:91673744-92274600
CIL_00080P CIL_00080P_0002 VISTA 8:91691197-92292386
CIL_00080L CIL_00080L_0002 VISTA 8:91725551-92327539
CIL_00080M CIL_00080M_0002 VISTA 8:91729339-92330277
CIL_00080N CIL_00080N_0002 VISTA 8:91758697-92359642
CIL_00080R CIL_00080R_0002 VISTA 8:91763820-92364618
CIL_0008KP CIL_0008KP_0002 VISTA 8:91765542-92366816
CIL_0008ZH CIL_0008ZH_0002 VISTA 8:91770441-92371690
CIL_0008ZE CIL_0008ZE_0002 VISTA 8:91794559-92395829
CIL_0006IA CIL_0006IA_0002 CGP 8:91798525-92361456

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001656 IEP metanephros development
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007498 IGI mesoderm development
GO:0030424 IDA axon
GO:0043565 IEA sequence-specific DNA binding
GO:0045665 IDA negative regulation of neuron differentiation
GO:0045666 IDA positive regulation of neuron differentiation
GO:0072047 IEP proximal/distal pattern formation involved in nephron development
GO:0072086 IEP specification of loop of Henle identity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031138 irx3b iroquois homeobox protein 3b protein_coding Danio_rerio
ENSDARG00000052947 irx3a iroquois homeobox protein 3a protein_coding Danio_rerio
ENSG00000177508 IRX3 iroquois homeobox 3 protein_coding Homo_sapiens

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