C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RIC8 guanine nucleotide exchange factor A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000177963 RIC8A 9606 + 11:207511-215113 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000325207 RIC8A-001 208530-215113 protein_coding
  ENST00000524854 RIC8A-016 212728-214557 protein_coding
  ENST00000526104 RIC8A-002 207511-215113 protein_coding
  ENST00000526557 RIC8A-014 213036-214516 retained_intron
  ENST00000526982 RIC8A-005 208800-210662 nonsense_mediated_decay
  ENST00000527039 RIC8A-012 209745-212591 retained_intron
  ENST00000527468 RIC8A-008 209080-209738 protein_coding
  ENST00000527696 RIC8A-003 209069-215113 protein_coding
  ENST00000527728 RIC8A-011 209630-212724 protein_coding
  ENST00000528357 RIC8A-009 208800-209791 protein_coding
  ENST00000529275 RIC8A-017 212870-214495 protein_coding
  ENST00000530149 RIC8A-004 210364-213780 retained_intron
  ENST00000530889 RIC8A-006 208841-209811 protein_coding
  ENST00000531541 RIC8A-015 213449-214556 processed_transcript
  ENST00000532241 RIC8A-013 212468-212916 retained_intron
  ENST00000532373 RIC8A-007 208837-209788 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000325207ENST00000524854ENST00000526104ENST00000527696ENST00000527728ENST00000530149
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000325207 7.244±0.00 19.667±0.00 1.028±0.00 8.016±0.00 8.364±6.73 8.768±0.00 6.736±5.79 10.477±9.45 3.720±2.73 6.305±0.00 14.679±0.00 12.008±9.16 6.840±1.50 16.415±8.51
ENST00000524854 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.220±0.00 N/A N/A N/A
ENST00000526104 15.298±0.00 11.921±0.00 1.741±0.00 5.955±3.44 8.309±0.00 2.606±1.19 N/A N/A 3.659±0.00 3.418±1.82 2.338±0.00 6.837±4.52 11.699±0.16 13.206±0.00
ENST00000527696 N/A N/A 2.791±0.00 2.457±0.00 N/A 2.483±0.00 0.229±0.00 N/A 1.059±0.00 N/A N/A 8.463±3.14 N/A N/A
ENST00000527728 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.956±0.00 N/A N/A N/A
ENST00000530149 N/A N/A N/A N/A 0.515±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006LA CIL_0006LA_0001 CGP 11:207511-236931

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IEA in utero embryonic development
GO:0001944 IEA vasculature development
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005737 ISS cytoplasm
GO:0005886 ISS plasma membrane
GO:0007193 IEA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007369 IEA gastrulation
GO:0008542 IEA visual learning
GO:0009416 IEA response to light stimulus
GO:0016020 IEA membrane
GO:0042074 IEA cell migration involved in gastrulation
GO:0043547 IEA positive regulation of GTPase activity
GO:0070586 IEA cell-cell adhesion involved in gastrulation
GO:0071711 IEA basement membrane organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007247 ric8a resistance to inhibitors of cholinesterase 8 homolog A protein_coding Danio_rerio
ENSMUSG00000025485 Ric8 resistance to inhibitors of cholinesterase 8 homolog (C. elegans) protein_coding Mus_musculus

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