C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: plectin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000178209 PLEC 9606 - 8:143915147-143976734 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000322810 PLEC-001 143915153-143950876 protein_coding
  ENST00000345136 PLEC-004 143915147-143939590 protein_coding
  ENST00000354589 PLEC-005 143915153-143943958 protein_coding
  ENST00000354958 PLEC-008 143915153-143953920 protein_coding
  ENST00000356346 PLEC-009 143915153-143973529 protein_coding
  ENST00000357649 PLEC-006 143915153-143942524 protein_coding
  ENST00000398774 PLEC-007 143915153-143944737 protein_coding
  ENST00000436759 PLEC-002 143915153-143976734 protein_coding
  ENST00000526416 PLEC-015 143935277-143946405 protein_coding
  ENST00000527096 PLEC-003 143916177-143975369 protein_coding
  ENST00000527303 PLEC-016 143921932-143927011 protein_coding
  ENST00000527816 PLEC-014 143935918-143946547 protein_coding
  ENST00000528025 PLEC-010 143932400-143975375 protein_coding
  ENST00000528131 PLEC-013 143935979-143958799 protein_coding
  ENST00000532346 PLEC-012 143937664-143975219 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000345136ENST00000354589ENST00000354958ENST00000356346ENST00000357649ENST00000398774ENST00000436759ENST00000527096
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000345136 N/A N/A 0.549±0.00 N/A 6.507±0.00 4.809±0.00 N/A N/A 3.477±0.00 N/A N/A 4.692±0.00 N/A N/A
ENST00000354589 N/A N/A N/A N/A 4.240±0.00 2.388±0.00 1.387±0.00 1.448±0.00 2.940±0.00 1.889±0.00 N/A N/A N/A 1.321±0.00
ENST00000354958 N/A N/A N/A 8.128±5.84 N/A 6.044±0.00 4.631±0.00 5.135±0.00 2.788±0.52 N/A N/A 14.765±12.24 N/A N/A
ENST00000356346 8.569±0.00 N/A N/A N/A N/A N/A 9.464±0.00 3.604±0.00 4.541±0.00 N/A N/A N/A 12.195±0.00 N/A
ENST00000357649 10.689±0.00 N/A N/A 5.499±0.00 3.848±0.00 N/A N/A N/A N/A N/A N/A 5.392±0.00 7.820±0.00 N/A
ENST00000398774 6.844±0.00 27.867±0.00 2.716±0.00 8.329±0.00 12.844±0.00 15.457±0.00 17.401±0.00 5.381±0.00 2.524±0.00 9.823±0.00 59.504±51.66 32.712±0.00 8.389±0.00 16.489±0.00
ENST00000436759 5.640±0.00 N/A N/A 9.188±0.00 N/A N/A N/A N/A N/A 5.115±0.00 N/A N/A N/A N/A
ENST00000527096 N/A N/A 0.585±0.00 3.767±3.12 N/A 3.480±0.00 1.293±0.00 N/A 2.283±0.00 2.562±0.00 3.916±0.00 5.087±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006FZ CIL_0006FZ_0002 CGP 8:143857324-143976734
CIL_0007SS CIL_0007SS_0001 VISTA 8:143880613-144482307
CIL_0002GS CIL_0002GS_0001 CGP 8:143915147-144012772

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 IEA actin binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0005886 NAS plasma membrane
GO:0005925 IDA focal adhesion
GO:0006915 TAS apoptotic process
GO:0006921 TAS cellular component disassembly involved in execution phase of apoptosis
GO:0008307 IMP structural constituent of muscle
GO:0016528 ISS sarcoplasm
GO:0030056 IDA hemidesmosome
GO:0030198 TAS extracellular matrix organization
GO:0030506 IPI ankyrin binding
GO:0031581 IDA hemidesmosome assembly
GO:0034329 TAS cell junction assembly
GO:0042383 IDA sarcolemma
GO:0043034 TAS costamere
GO:0043292 IEA contractile fiber
GO:0044822 IDA poly(A) RNA binding
GO:0045111 IDA intermediate filament cytoskeleton
GO:0046417 IEA chorismate metabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021987 plecb plectin b protein_coding Danio_rerio
ENSDARG00000062590 pleca plectin a protein_coding Danio_rerio
ENSMUSG00000022565 Plec plectin protein_coding Mus_musculus

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