C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: period circadian clock 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000179094 PER1 9606 - 17:8140472-8156506 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000317276 PER1-001 8140472-8152435 protein_coding
  ENST00000354903 PER1-002 8144055-8156360 protein_coding
  ENST00000577253 PER1-008 8150050-8156405 protein_coding
  ENST00000577424 PER1-013 8146869-8147582 retained_intron
  ENST00000578089 PER1-015 8143441-8146488 processed_transcript
  ENST00000578223 PER1-011 8147548-8148989 retained_intron
  ENST00000578950 PER1-018 8143757-8145170 retained_intron
  ENST00000579065 PER1-004 8149239-8152383 retained_intron
  ENST00000579098 PER1-017 8142548-8143344 retained_intron
  ENST00000579203 PER1-012 8147259-8148005 retained_intron
  ENST00000581082 PER1-005 8140477-8150832 protein_coding
  ENST00000581395 PER1-003 8144056-8156506 nonsense_mediated_decay
  ENST00000581703 PER1-009 8149975-8152435 protein_coding
  ENST00000582719 PER1-006 8140800-8152344 nonsense_mediated_decay
  ENST00000583559 PER1-016 8144056-8146024 protein_coding
  ENST00000583677 PER1-007 8141216-8142191 retained_intron
  ENST00000584202 PER1-010 8150256-8156355 protein_coding
  ENST00000585095 PER1-014 8146640-8147549 retained_intron
  ENST00000585284 PER1-019 8141233-8142470 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000317276ENST00000354903ENST00000581082ENST00000582719ENST00000585284
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000317276 39.595±0.00 19.871±0.00 N/A 2.166±0.00 12.728±0.00 8.944±0.00 11.160±0.00 2.592±0.00 6.503±0.00 11.139±8.57 10.914±8.23 24.407±12.83 10.572±4.46 12.131±2.29
ENST00000354903 N/A N/A N/A N/A N/A N/A 0.756±0.00 N/A N/A 1.211±0.00 N/A 1.571±0.00 N/A N/A
ENST00000581082 21.704±0.00 18.639±0.00 1.192±0.00 N/A 11.713±0.00 18.932±0.00 8.827±0.00 10.924±0.00 N/A 13.078±0.00 20.405±0.00 N/A 4.207±0.00 17.725±0.00
ENST00000582719 N/A N/A N/A N/A 1.098±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000585284 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 47.311±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000976 IEA transcription regulatory region sequence-specific DNA binding
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000989 ISS transcription factor binding transcription factor activity
GO:0002028 ISS regulation of sodium ion transport
GO:0004871 IEA signal transducer activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007165 IEA signal transduction
GO:0007623 IEP circadian rhythm
GO:0008134 IEA transcription factor binding
GO:0009416 IEA response to light stimulus
GO:0009649 TAS entrainment of circadian clock
GO:0010608 ISS posttranscriptional regulation of gene expression
GO:0019900 IPI kinase binding
GO:0031490 ISS chromatin DNA binding
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032922 IDA circadian regulation of gene expression
GO:0042634 IMP regulation of hair cycle
GO:0042752 ISS regulation of circadian rhythm
GO:0043124 ISS negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043153 ISS entrainment of circadian clock by photoperiod
GO:0043966 IDA histone H3 acetylation
GO:0043967 IDA histone H4 acetylation
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046329 ISS negative regulation of JNK cascade
GO:0051591 IEA response to cAMP
GO:0070888 IDA E-box binding
GO:0070932 ISS histone H3 deacetylation
GO:0097167 ISS circadian regulation of translation
GO:1900015 ISS regulation of cytokine production involved in inflammatory response
GO:1900744 ISS regulation of p38MAPK cascade
GO:2000323 ISS negative regulation of glucocorticoid receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012499 per1b period homolog 1b (Drosophila) protein_coding Danio_rerio
ENSDARG00000056885 per1a period homolog 1a (Drosophila) protein_coding Danio_rerio
ENSMUSG00000020893 Per1 period circadian clock 1 protein_coding Mus_musculus

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