C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: period circadian clock 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020893 Per1 10090 + 11:69095217-69109960 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021271 Per1-001 69098948-69109960 protein_coding
  ENSMUST00000101004 Per1-003 69095217-69106458 protein_coding
  ENSMUST00000102605 Per1-002 69100522-69109960 protein_coding
  ENSMUST00000132462 Per1-005 69100152-69101048 protein_coding
  ENSMUST00000142392 Per1-004 69100509-69106296 nonsense_mediated_decay
  ENSMUST00000166748 Per1-201 69100158-69109948 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021271ENSMUST00000101004ENSMUST00000102605ENSMUST00000166748
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021271 5.214±3.48 9.239±3.40 8.866±0.73 3.464±0.06 5.560±2.47 2.394±1.18 3.478±1.93 2.163±0.77 1.403±1.38 11.869±7.25 7.218±2.81 3.844±2.52 2.201±0.65 29.161±1.17
ENSMUST00000101004 4.359±2.06 6.929±2.37 3.008±0.68 1.006±0.21 4.661±1.75 2.000±0.80 2.451±1.19 1.155±0.00 0.717±0.66 9.766±5.84 2.394±1.25 4.202±2.39 2.894±1.71 14.348±1.21
ENSMUST00000102605 N/A N/A N/A 1.183±0.00 N/A 0.916±0.00 N/A N/A N/A N/A N/A N/A 1.404±0.00 N/A
ENSMUST00000166748 N/A N/A N/A 3.352±2.62 1.712±0.44 2.137±1.01 1.384±0.00 N/A 0.648±0.00 1.405±0.00 N/A 4.265±2.37 7.456±6.38 4.931±0.47

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000976 IDA transcription regulatory region sequence-specific DNA binding
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000989 IDA transcription factor binding transcription factor activity
GO:0002028 IMP regulation of sodium ion transport
GO:0004871 IEA signal transducer activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0007165 IEA signal transduction
GO:0007623 TAS circadian rhythm
GO:0008134 IPI transcription factor binding
GO:0009416 IEP response to light stimulus
GO:0010608 IMP posttranscriptional regulation of gene expression
GO:0019900 IPI kinase binding
GO:0031490 IDA chromatin DNA binding
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032922 ISS circadian regulation of gene expression
GO:0042634 ISS regulation of hair cycle
GO:0042752 IMP regulation of circadian rhythm
GO:0043124 ISS negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043153 IMP entrainment of circadian clock by photoperiod
GO:0043966 IDA histone H3 acetylation
GO:0043967 IEA histone H4 acetylation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046329 ISS negative regulation of JNK cascade
GO:0051591 IDA response to cAMP
GO:0070888 IEA E-box binding
GO:0070932 IMP histone H3 deacetylation
GO:0097167 IMP circadian regulation of translation
GO:1900015 ISS regulation of cytokine production involved in inflammatory response
GO:1900744 ISS regulation of p38MAPK cascade
GO:2000323 IMP negative regulation of glucocorticoid receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012499 per1b period homolog 1b (Drosophila) protein_coding Danio_rerio
ENSDARG00000056885 per1a period homolog 1a (Drosophila) protein_coding Danio_rerio
ENSG00000179094 PER1 period circadian clock 1 protein_coding Homo_sapiens

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