C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cell adhesion molecule 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000182985 CADM1 9606 - 11:115169218-115504957 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000331581 CADM1-003 115176295-115504565 protein_coding
  ENST00000441886 CADM1-017 115190609-115214694 processed_transcript
  ENST00000452722 CADM1-001 115169236-115504415 protein_coding
  ENST00000536727 CADM1-006 115174307-115504415 protein_coding
  ENST00000536781 CADM1-012 115399084-115504415 processed_transcript
  ENST00000537058 CADM1-005 115174307-115504415 protein_coding
  ENST00000537140 CADM1-004 115169236-115504523 processed_transcript
  ENST00000540373 CADM1-016 115214699-115218144 retained_intron
  ENST00000540852 CADM1-018 115176408-115191046 retained_intron
  ENST00000540951 CADM1-021 115231440-115504415 nonsense_mediated_decay
  ENST00000541434 CADM1-007 115214490-115504394 retained_intron
  ENST00000542447 CADM1-002 115173625-115504523 protein_coding
  ENST00000542450 CADM1-015 115217940-115240980 protein_coding
  ENST00000543249 CADM1-010 115229220-115504957 protein_coding
  ENST00000543375 CADM1-020 115176330-115194110 processed_transcript
  ENST00000543540 CADM1-013 115229156-115287477 protein_coding
  ENST00000545094 CADM1-014 115229189-115256891 protein_coding
  ENST00000545380 CADM1-008 115175341-115504389 protein_coding
  ENST00000545960 CADM1-011 115169218-115198440 processed_transcript
  ENST00000546000 CADM1-019 115176327-115179111 retained_intron
  ENST00000612235 CADM1-201 115169589-115240422 protein_coding
  ENST00000612471 CADM1-202 115173626-115240421 protein_coding
  ENST00000616271 CADM1-203 115176467-115240421 protein_coding
  ENST00000621043 CADM1-204 115176467-115240421 protein_coding
  ENST00000621709 CADM1-205 115173626-115240421 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000331581ENST00000536727ENST00000537058ENST00000541434ENST00000542447ENST00000542450ENST00000543249ENST00000545380ENST00000612471ENST00000616271ENST00000621709
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000331581 N/A N/A N/A 6.721±0.00 N/A N/A N/A 8.000±0.00 4.065±2.26 N/A N/A N/A N/A N/A
ENST00000536727 N/A N/A N/A 6.660±0.00 N/A 0.506±0.00 N/A N/A N/A N/A N/A N/A N/A 7.861±0.00
ENST00000537058 0.595±0.00 N/A 1.309±0.00 N/A 1.516±0.00 0.613±0.00 1.544±0.00 N/A N/A 6.201±0.00 N/A 1.829±0.00 3.801±0.00 N/A
ENST00000541434 N/A N/A 4.223±0.00 N/A N/A N/A 3.243±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000542447 N/A N/A 0.866±0.00 5.771±2.07 1.406±0.00 N/A 0.939±0.00 3.305±0.00 1.299±0.00 7.738±1.34 N/A 2.124±0.00 2.436±0.30 5.374±0.00
ENST00000542450 N/A N/A N/A N/A N/A 1.452±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000543249 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.746±0.00 N/A N/A
ENST00000545380 N/A N/A N/A N/A 1.515±0.00 N/A 1.520±0.21 N/A 2.301±0.00 N/A N/A 2.564±1.29 20.006±0.00 29.038±0.00
ENST00000612471 N/A N/A N/A 3.884±0.00 N/A 1.192±0.00 2.385±0.00 1.299±0.00 N/A N/A 0.602±0.52 N/A N/A N/A
ENST00000616271 N/A N/A N/A N/A N/A N/A N/A 7.822±0.00 5.972±0.00 N/A N/A N/A N/A 8.237±0.00
ENST00000621709 1.552±0.00 2.793±0.00 2.814±0.00 10.317±0.00 1.677±0.82 2.447±2.19 1.503±0.81 4.754±0.25 1.830±0.09 8.144±2.37 0.433±0.00 2.541±1.75 8.230±2.23 6.254±0.44

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007JB CIL_0007JB_0003 UCNEbase 11:114879628-115317708

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001889 IEA liver development
GO:0005102 ISS receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005886 IDA plasma membrane
GO:0005911 ISS cell-cell junction
GO:0006915 IEA apoptotic process
GO:0007155 IEA cell adhesion
GO:0007156 ISS homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007157 ISS heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007283 IEA spermatogenesis
GO:0007416 IEA synapse assembly
GO:0007420 IEA brain development
GO:0008021 IEA synaptic vesicle
GO:0008037 ISS cell recognition
GO:0009826 IEA unidimensional cell growth
GO:0016021 IEA integral component of membrane
GO:0016323 ISS basolateral plasma membrane
GO:0016338 IEA calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
GO:0030154 IEA cell differentiation
GO:0030165 ISS PDZ domain binding
GO:0030424 IEA axon
GO:0030425 IEA dendrite
GO:0034329 TAS cell junction assembly
GO:0034332 TAS adherens junction organization
GO:0042271 ISS susceptibility to natural killer cell mediated cytotoxicity
GO:0042803 ISS protein homodimerization activity
GO:0043005 IEA neuron projection
GO:0045202 IEA synapse
GO:0045216 TAS cell-cell junction organization
GO:0045954 ISS positive regulation of natural killer cell mediated cytotoxicity
GO:0050715 IDA positive regulation of cytokine secretion
GO:0050839 IEA cell adhesion molecule binding
GO:0051606 ISS detection of stimulus
GO:0060348 IEA bone development
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031075 cadm1a cell adhesion molecule 1a protein_coding Danio_rerio
ENSDARG00000042677 cadm1b cell adhesion molecule 1b protein_coding Danio_rerio
ENSMUSG00000032076 Cadm1 cell adhesion molecule 1 protein_coding Mus_musculus

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