C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: BRCA1/BRCA2-containing complex, subunit 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185515 BRCC3 9606 + X:155071420-155123074 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000330045 BRCC3-002 155071431-155122727 protein_coding
  ENST00000340647 BRCC3-006 155071420-155121318 protein_coding
  ENST00000369459 BRCC3-004 155071499-155123072 protein_coding
  ENST00000369462 BRCC3-001 155071503-155123074 protein_coding
  ENST00000399026 BRCC3-003 155073411-155078930 protein_coding
  ENST00000399042 BRCC3-201 155071528-155120150 protein_coding
  ENST00000411985 BRCC3-007 155071518-155116183 protein_coding
  ENST00000453705 BRCC3-005 155071532-155123036 nonsense_mediated_decay
  ENST00000620502 BRCC3-202 155071528-155120150 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000330045ENST00000340647ENST00000369459ENST00000369462ENST00000453705ENST00000620502
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000330045 N/A 2.341±0.00 0.647±0.00 0.962±0.00 3.207±0.00 0.478±0.00 N/A 0.796±0.00 N/A N/A 1.358±0.00 N/A N/A
ENST00000340647 N/A N/A 1.025±0.00 N/A 1.550±0.00 N/A N/A N/A N/A 1.658±0.00 N/A N/A N/A
ENST00000369459 N/A N/A 0.830±0.57 1.049±0.00 2.130±0.00 3.568±0.00 N/A 0.871±0.00 0.190±0.00 2.219±0.00 N/A 2.482±0.00 1.584±0.00
ENST00000369462 N/A N/A N/A 1.482±0.14 N/A 0.180±0.00 4.685±0.00 0.449±0.00 N/A N/A 1.784±0.64 1.752±0.44 0.187±0.00
ENST00000453705 1.677±0.00 N/A 0.498±0.00 N/A 0.960±0.00 N/A N/A N/A 0.496±0.00 0.872±0.07 1.573±0.29 2.587±0.28 0.328±0.00
ENST00000620502 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.699±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007GE CIL_0007GE_0002 CGP X:155061622-155123074
CIL_0003LJ CIL_0003LJ_0001 CGP X:155071420-155239817

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000151 IDA ubiquitin ligase complex
GO:0000152 IDA nuclear ubiquitin ligase complex
GO:0004221 IMP ubiquitin thiolesterase activity
GO:0004843 IMP ubiquitin-specific protease activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0006302 IMP double-strand break repair
GO:0006508 IEA proteolysis
GO:0008237 IMP metallopeptidase activity
GO:0010165 IDA response to X-ray
GO:0010212 IMP response to ionizing radiation
GO:0030234 IDA enzyme regulator activity
GO:0031572 IMP G2 DNA damage checkpoint
GO:0031593 IDA polyubiquitin binding
GO:0045739 IMP positive regulation of DNA repair
GO:0046872 IEA metal ion binding
GO:0050790 IDA regulation of catalytic activity
GO:0070531 IDA BRCA1-A complex
GO:0070536 IDA protein K63-linked deubiquitination
GO:0070537 IDA histone H2A K63-linked deubiquitination
GO:0070552 IDA BRISC complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078456 brcc3 BRCA1/BRCA2-containing complex, subunit 3 protein_coding Danio_rerio
ENSMUSG00000031201 Brcc3 BRCA1/BRCA2-containing complex, subunit 3 protein_coding Mus_musculus

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