C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: BRCA1/BRCA2-containing complex, subunit 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000369459 BRCC3-004 ENSG00000185515 9606 + X:155071499-155123072 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartLiverLungMusclePlacentaTestisENST00000369459
Transcript ID Brain Breast Colon Heart Liver Lung Muscle Placenta Testis
ENST00000369459 0.830±0.57 1.049±0.00 2.130±0.00 3.568±0.00 0.871±0.00 0.190±0.00 2.219±0.00 2.482±0.00 1.584±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007GE CIL_0007GE_0002 CGP X:155061622-155123074
CIL_0003LJ CIL_0003LJ_0001 CGP X:155071420-155239817

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000151 IDA ubiquitin ligase complex
GO:0000152 IDA nuclear ubiquitin ligase complex
GO:0004221 IMP ubiquitin thiolesterase activity
GO:0004843 IMP ubiquitin-specific protease activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0006302 IMP double-strand break repair
GO:0006508 IEA proteolysis
GO:0008237 IMP metallopeptidase activity
GO:0010165 IDA response to X-ray
GO:0010212 IMP response to ionizing radiation
GO:0030234 IDA enzyme regulator activity
GO:0031572 IMP G2 DNA damage checkpoint
GO:0031593 IDA polyubiquitin binding
GO:0045739 IMP positive regulation of DNA repair
GO:0046872 IEA metal ion binding
GO:0050790 IDA regulation of catalytic activity
GO:0070531 IDA BRCA1-A complex
GO:0070536 IDA protein K63-linked deubiquitination
GO:0070537 IDA histone H2A K63-linked deubiquitination
GO:0070552 IDA BRISC complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000118428 Brcc3-008 protein_coding Mus_musculus 0 1112
ENSMUST00000114074 Brcc3-004 protein_coding Mus_musculus 0 774
ENSMUST00000033544 Brcc3-001 protein_coding Mus_musculus 0 774
ENSMUST00000151938 Brcc3-003 retained_intron Mus_musculus 0 580
ENSMUST00000133781 Brcc3-007 protein_coding Mus_musculus 0 520
ENSMUST00000117333 Gm12598-001 processed_pseudogene Mus_musculus 0 507
ENSMUST00000124321 Brcc3-005 retained_intron Mus_musculus 0 359
ENSMUST00000152228 Brcc3-006 protein_coding Mus_musculus 0 257

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