C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 2, subfamily R, polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000186104 CYP2R1 9606 - 11:14877440-14892252 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000334636 CYP2R1-001 14877440-14892252 protein_coding
  ENST00000525015 CYP2R1-006 14878012-14885841 nonsense_mediated_decay
  ENST00000526276 CYP2R1-008 14880315-14891492 processed_transcript
  ENST00000526489 CYP2R1-009 14880135-14890531 processed_transcript
  ENST00000529043 CYP2R1-007 14880634-14891530 processed_transcript
  ENST00000530609 CYP2R1-004 14878009-14891640 nonsense_mediated_decay
  ENST00000532378 CYP2R1-003 14878038-14891651 protein_coding
  ENST00000532641 CYP2R1-010 14880337-14885977 processed_transcript
  ENST00000532805 CYP2R1-005 14878007-14887334 nonsense_mediated_decay
  ENST00000534686 CYP2R1-002 14878009-14891662 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000334636ENST00000525015ENST00000526489ENST00000529043ENST00000530609ENST00000532378ENST00000532641ENST00000532805ENST00000534686
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000334636 N/A N/A N/A N/A N/A 0.913±0.00 0.173±0.00 N/A 0.191±0.00 N/A N/A 0.363±0.00 N/A N/A
ENST00000525015 2.396±0.00 N/A N/A 2.525±0.00 N/A N/A N/A 2.252±0.00 2.416±0.00 1.381±0.00 N/A 3.430±0.39 1.141±0.00 9.252±0.00
ENST00000526489 N/A N/A N/A 0.670±0.00 1.119±0.00 1.005±0.00 N/A 1.290±0.00 N/A 1.065±0.00 0.332±0.00 1.647±0.00 0.522±0.00 3.250±0.00
ENST00000529043 N/A N/A 2.360±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000530609 N/A 1.733±0.00 N/A N/A 0.581±0.00 0.853±0.00 0.273±0.00 N/A 0.502±0.00 N/A N/A 1.234±0.00 0.688±0.19 3.940±0.51
ENST00000532378 0.883±0.00 2.132±0.00 N/A 0.426±0.00 1.109±0.00 0.447±0.00 0.792±0.00 1.115±0.00 0.424±0.03 0.733±0.00 0.527±0.00 2.039±1.03 0.673±0.45 4.206±1.69
ENST00000532641 N/A N/A N/A N/A N/A N/A N/A N/A 1.205±0.00 N/A 0.406±0.00 2.263±0.00 N/A N/A
ENST00000532805 N/A 0.910±0.00 0.878±0.00 0.613±0.00 N/A N/A 0.159±0.00 0.384±0.00 0.346±0.14 1.364±0.00 N/A N/A N/A N/A
ENST00000534686 0.555±0.00 N/A N/A 0.593±0.00 N/A 0.528±0.00 0.392±0.00 0.835±0.00 N/A N/A 0.507±0.00 1.053±0.10 0.232±0.00 2.314±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003ZS CIL_0003ZS_0001 CGP 11:14643723-14892252
CIL_000419 CIL_000419_0002 CGP 11:14877440-15082342

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004497 IEA monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006766 TAS vitamin metabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0008202 TAS steroid metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 IEA heme binding
GO:0030343 IEA vitamin D3 25-hydroxylase activity
GO:0036378 IEA calcitriol biosynthetic process from calciol
GO:0042359 TAS vitamin D metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056587 cyp2r1 cytochrome P450, family 2, subfamily R, polypeptide 1 protein_coding Danio_rerio
ENSMUSG00000030670 Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 protein_coding Mus_musculus

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