C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 1, catalytic subunit, gamma isozyme
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000186298 PPP1CC 9606 - 12:110719680-110742939 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000335007 PPP1CC-001 110719680-110742898 protein_coding
  ENST00000340766 PPP1CC-002 110719908-110742939 protein_coding
  ENST00000546904 PPP1CC-008 110720366-110722467 retained_intron
  ENST00000546933 PPP1CC-004 110720921-110732983 protein_coding
  ENST00000550261 PPP1CC-005 110719983-110730755 nonsense_mediated_decay
  ENST00000550991 PPP1CC-010 110721301-110742873 protein_coding
  ENST00000551582 PPP1CC-007 110720730-110724714 protein_coding
  ENST00000551676 PPP1CC-009 110721770-110742839 protein_coding
  ENST00000551690 PPP1CC-003 110731816-110742900 processed_transcript
  ENST00000553024 PPP1CC-006 110720748-110726679 retained_intron
  ENST00000620030 PPP1CC-011 110730525-110742867 non_stop_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000335007ENST00000340766ENST00000546904ENST00000546933ENST00000550261ENST00000550991ENST00000551582ENST00000551676
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000335007 21.267±0.00 7.699±0.00 2.492±0.00 7.812±0.95 20.333±10.99 16.378±2.84 11.028±2.59 4.436±0.29 10.253±8.49 6.852±0.00 8.182±3.39 28.091±8.79 17.759±4.34 29.330±0.00
ENST00000340766 12.672±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.608±0.00 22.366±3.71 7.603±0.00 71.642±39.42
ENST00000546904 N/A N/A N/A N/A 10.028±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000546933 N/A N/A N/A N/A N/A N/A N/A 1.220±0.00 N/A N/A N/A N/A N/A N/A
ENST00000550261 24.334±0.00 34.944±0.00 N/A 32.401±0.00 30.742±0.00 53.190±0.00 46.785±0.00 26.001±0.00 9.164±0.00 N/A 48.832±0.00 61.953±0.00 34.512±0.00 90.333±39.08
ENST00000550991 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.564±0.00 N/A N/A N/A N/A
ENST00000551582 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 40.376±0.00 17.529±0.00 N/A
ENST00000551676 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.149±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008YU CIL_0008YU_0001 VISTA 12:110628804-111231731

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000278 TAS mitotic cell cycle
GO:0000776 IEA kinetochore
GO:0004721 TAS phosphoprotein phosphatase activity
GO:0004722 IMP protein serine/threonine phosphatase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005829 TAS cytosol
GO:0005925 IDA focal adhesion
GO:0005977 IEA glycogen metabolic process
GO:0006470 ISS protein dephosphorylation
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0008152 IEA metabolic process
GO:0016311 IEA dephosphorylation
GO:0016787 IEA hydrolase activity
GO:0016791 ISS phosphatase activity
GO:0019433 TAS triglyceride catabolic process
GO:0019901 IPI protein kinase binding
GO:0030512 TAS negative regulation of transforming growth factor beta receptor signaling pathway
GO:0032922 ISS circadian regulation of gene expression
GO:0042752 IMP regulation of circadian rhythm
GO:0043153 ISS entrainment of circadian clock by photoperiod
GO:0043234 IMP protein complex
GO:0044281 TAS small molecule metabolic process
GO:0044822 IDA poly(A) RNA binding
GO:0046872 IEA metal ion binding
GO:0047485 IPI protein N-terminus binding
GO:0051301 IEA cell division
GO:0070688 IDA MLL5-L complex
GO:0072357 IDA PTW/PP1 phosphatase complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090779 ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform protein_coding Danio_rerio
ENSMUSG00000004455 Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform protein_coding Mus_musculus

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