C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: L1 cell adhesion molecule
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198910 L1CAM 9606 - X:153861514-153909223 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361699 L1CAM-002 153862548-153875847 protein_coding
  ENST00000361981 L1CAM-201 153861514-153875944 protein_coding
  ENST00000370055 L1CAM-006 153861953-153886154 protein_coding
  ENST00000370058 L1CAM-003 153862433-153864478 protein_coding
  ENST00000370060 L1CAM-001 153861514-153886146 protein_coding
  ENST00000407935 L1CAM-017 153872152-153876027 protein_coding
  ENST00000420165 L1CAM-008 153872267-153886173 protein_coding
  ENST00000439496 L1CAM-011 153871128-153876039 protein_coding
  ENST00000455590 L1CAM-007 153866772-153868377 protein_coding
  ENST00000458029 L1CAM-010 153872301-153876391 protein_coding
  ENST00000460553 L1CAM-009 153872949-153886142 retained_intron
  ENST00000464967 L1CAM-016 153872221-153909223 retained_intron
  ENST00000474853 L1CAM-014 153864964-153865915 retained_intron
  ENST00000484652 L1CAM-012 153868407-153869172 retained_intron
  ENST00000491983 L1CAM-015 153862792-153863969 retained_intron
  ENST00000496122 L1CAM-013 153867551-153868623 retained_intron
  ENST00000616195 L1CAM-005 153883864-153886161 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartKidneyLiverOvaryPlacentaTestisENST00000361699ENST00000361981ENST00000370055ENST00000370060
Transcript ID Bladder Brain Breast Colon Heart Kidney Liver Ovary Placenta Testis
ENST00000361699 1.776±0.00 3.572±0.00 1.877±0.00 1.307±0.00 0.357±0.00 N/A N/A 2.012±0.00 N/A N/A
ENST00000361981 0.585±0.00 N/A N/A N/A 2.068±0.00 9.047±0.00 N/A 7.236±6.17 3.121±0.00 2.115±0.00
ENST00000370055 N/A N/A N/A 18.723±0.00 N/A 12.570±0.00 1.015±0.00 N/A N/A N/A
ENST00000370060 N/A 13.923±6.31 N/A 8.138±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001US CIL_0001US_0001 CGP X:153802166-153909223

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005178 IEA integrin binding
GO:0005515 IEA protein binding
GO:0005886 TAS plasma membrane
GO:0005925 IDA focal adhesion
GO:0006935 TAS chemotaxis
GO:0007155 NAS cell adhesion
GO:0007156 IEA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007157 IEA heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007159 IEA leukocyte cell-cell adhesion
GO:0007166 IEA cell surface receptor signaling pathway
GO:0007399 TAS nervous system development
GO:0007411 TAS axon guidance
GO:0007596 TAS blood coagulation
GO:0008219 IEA cell death
GO:0009897 IEA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0022409 IEA positive regulation of cell-cell adhesion
GO:0031175 IEA neuron projection development
GO:0033631 IEA cell-cell adhesion mediated by integrin
GO:0033691 IEA sialic acid binding
GO:0034109 IEA homotypic cell-cell adhesion
GO:0042734 IEA presynaptic membrane
GO:0042802 IEA identical protein binding
GO:0043195 IEA terminal bouton
GO:0043621 IEA protein self-association
GO:0050850 IEA positive regulation of calcium-mediated signaling
GO:0050900 TAS leukocyte migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007149 nadl1.2 neural adhesion molecule L1.2 protein_coding Danio_rerio
ENSDARG00000015025 nadl1.1 neural adhesion molecule L1.1 protein_coding Danio_rerio
ENSMUSG00000031391 L1cam L1 cell adhesion molecule protein_coding Mus_musculus

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