C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: POU class 3 homeobox 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198914 POU3F3 9606 + 2:104855511-104860471 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361360 POU3F3-001 104855511-104860471 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000361360
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000361360 0.539±0.00 0.020±0.00 6.904±0.00 7.197±2.17 0.027±0.00 0.267±0.16 0.045±0.00 18.250±0.00 0.149±0.00 0.004±0.00 0.020±0.01 0.020±0.01 0.987±0.91

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004IW CIL_0004IW_0002 CGP 2:102736908-104860471
CIL_0007JQ CIL_0007JQ_0001 UCNEbase 2:102922366-105081592
CIL_0007ZQ CIL_0007ZQ_0001 VISTA 2:104271403-104872401
CIL_0008TY CIL_0008TY_0001 VISTA 2:104337637-104939940
CIL_0008JA CIL_0008JA_0001 VISTA 2:104383886-104985199
CIL_0008IN CIL_0008IN_0001 VISTA 2:104401122-105003398
CIL_0008O2 CIL_0008O2_0001 VISTA 2:104536515-105137711
CIL_0008KZ CIL_0008KZ_0001 VISTA 2:104548528-105151080
CIL_000902 CIL_000902_0001 VISTA 2:104600279-105202032
CIL_00096O CIL_00096O_0001 VISTA 2:104780753-105381700
CIL_0004II CIL_0004II_0002 CGP 2:104855511-105099960

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001822 IEA kidney development
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007417 TAS central nervous system development
GO:0008284 ISS positive regulation of cell proliferation
GO:0010628 ISS positive regulation of gene expression
GO:0021799 IEA cerebral cortex radially oriented cell migration
GO:0021869 IEA forebrain ventricular zone progenitor cell division
GO:0043066 ISS negative regulation of apoptotic process
GO:0043565 ISS sequence-specific DNA binding
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0071837 IEA HMG box domain binding
GO:0072218 ISS metanephric ascending thin limb development
GO:0072227 ISS metanephric macula densa development
GO:0072233 ISS metanephric thick ascending limb development
GO:0072236 ISS metanephric loop of Henle development
GO:0072240 ISS metanephric DCT cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042032 pou3f3a POU class 3 homeobox 3a protein_coding Danio_rerio
ENSDARG00000095896 pou3f3b POU class 3 homeobox 3b protein_coding Danio_rerio
ENSMUSG00000045515 Pou3f3 POU domain, class 3, transcription factor 3 protein_coding Mus_musculus

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