C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: POU domain, class 3, transcription factor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000045515 Pou3f3 10090 + 1:42695768-42703176 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000054883 Pou3f3-001 42695768-42703176 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000054883
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000054883 0.017±0.01 0.012±0.00 0.104±0.00 24.597±16.91 0.011±0.00 0.368±0.05 0.004±0.00 6.809±0.79 0.024±0.04 0.056±0.01 0.006±0.00 0.216±0.10 0.031±0.02 0.111±0.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004IW CIL_0004IW_0003 CGP 1:40805601-42703176
CIL_0007JQ CIL_0007JQ_0002 UCNEbase 1:40943211-42889148
CIL_0007ZQ CIL_0007ZQ_0002 VISTA 1:42123141-42724011
CIL_0008TY CIL_0008TY_0002 VISTA 1:42171587-42773853
CIL_0008JA CIL_0008JA_0002 VISTA 1:42221380-42823862
CIL_0008IN CIL_0008IN_0002 VISTA 1:42238719-42841030
CIL_0008O2 CIL_0008O2_0002 VISTA 1:42378245-42979419
CIL_0008KZ CIL_0008KZ_0002 VISTA 1:42390175-42992711
CIL_000902 CIL_000902_0002 VISTA 1:42440655-43042396
CIL_00096O CIL_00096O_0002 VISTA 1:42588323-43189246
CIL_0004II CIL_0004II_0003 CGP 1:42695768-42905682

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISO negative regulation of transcription from RNA polymerase II promoter
GO:0001822 IMP kidney development
GO:0003677 IDA DNA binding
GO:0003705 ISO RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0006366 ISO transcription from RNA polymerase II promoter
GO:0008284 IMP positive regulation of cell proliferation
GO:0021799 IGI cerebral cortex radially oriented cell migration
GO:0021869 IGI forebrain ventricular zone progenitor cell division
GO:0043066 IMP negative regulation of apoptotic process
GO:0043565 IDA sequence-specific DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0071837 IPI HMG box domain binding
GO:0072218 IMP metanephric ascending thin limb development
GO:0072227 IMP metanephric macula densa development
GO:0072233 IMP metanephric thick ascending limb development
GO:0072236 IMP metanephric loop of Henle development
GO:0072240 IMP metanephric DCT cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042032 pou3f3a POU class 3 homeobox 3a protein_coding Danio_rerio
ENSDARG00000095896 pou3f3b POU class 3 homeobox 3b protein_coding Danio_rerio
ENSG00000198914 POU3F3 POU class 3 homeobox 3 protein_coding Homo_sapiens

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