C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: deoxyribonuclease I
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000213918 DNASE1 9606 + 16:3611728-3680143 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000246949 DNASE1-001 3651837-3658095 protein_coding
  ENST00000407479 DNASE1-005 3642938-3665472 protein_coding
  ENST00000570376 DNASE1-010 3654860-3657047 nonsense_mediated_decay
  ENST00000570520 DNASE1-009 3654826-3656056 retained_intron
  ENST00000570664 DNASE1-016 3656711-3658095 protein_coding
  ENST00000570761 DNASE1-008 3642938-3652114 processed_transcript
  ENST00000570769 DNASE1-006 3611728-3658095 nonsense_mediated_decay
  ENST00000570807 DNASE1-012 3656119-3658088 nonsense_mediated_decay
  ENST00000571460 DNASE1-002 3654667-3663726 nonsense_mediated_decay
  ENST00000572237 DNASE1-013 3656164-3657857 nonsense_mediated_decay
  ENST00000573804 DNASE1-011 3656070-3657744 retained_intron
  ENST00000575479 DNASE1-015 3657272-3680143 protein_coding
  ENST00000576050 DNASE1-007 3642880-3657827 nonsense_mediated_decay
  ENST00000576792 DNASE1-014 3657250-3658207 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalColonKidneyOvaryENST00000407479
Transcript ID Adrenal Colon Kidney Ovary
ENST00000407479 0.941±0.00 0.567±0.00 2.647±0.00 1.383±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000AY CIL_0000AY_0001 CGP 16:3581181-3680143
CIL_0000ON CIL_0000ON_0001 CGP 16:3611728-3717597

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000737 IEA DNA catabolic process, endonucleolytic
GO:0003779 IEA actin binding
GO:0004530 IEA deoxyribonuclease I activity
GO:0004536 IEA deoxyribonuclease activity
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005634 IEA nucleus
GO:0006308 IEA DNA catabolic process
GO:0006915 IEA apoptotic process
GO:0016888 IEA endodeoxyribonuclease activity, producing 5'-phosphomonoesters
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012539 dnase1 deoxyribonuclease I protein_coding Danio_rerio
ENSMUSG00000005980 Dnase1 deoxyribonuclease I protein_coding Mus_musculus

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