C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: excision repair cross-complementation group 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000355832 ERCC6-001 ENSG00000225830 9606 - 10:49455368-49539026 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355832
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355832 0.224±0.00 0.463±0.00 0.393±0.15 0.346±0.00 0.769±0.00 0.467±0.09 1.221±0.06 0.964±0.76 0.371±0.10 0.702±0.42 0.731±0.51 0.744±0.61 0.904±0.23

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008ZL CIL_0008ZL_0001 VISTA 10:48905403-49506260
CIL_00084A CIL_00084A_0001 VISTA 10:49095759-49697208
CIL_0007OS CIL_0007OS_0002 UCNEbase 10:49372114-49500701

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000303 IEA response to superoxide
GO:0003677 IDA:IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 IDA nucleoplasm
GO:0005730 IDA nucleolus
GO:0006200 IDA ATP catabolic process
GO:0006281 TAS DNA repair
GO:0006283 IMP transcription-coupled nucleotide-excision repair
GO:0006284 IMP base-excision repair
GO:0006289 TAS nucleotide-excision repair
GO:0006290 IEA pyrimidine dimer repair
GO:0006362 IEA transcription elongation from RNA polymerase I promoter
GO:0006366 NAS transcription from RNA polymerase II promoter
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0006979 IDA response to oxidative stress
GO:0007256 IEA activation of JNKK activity
GO:0007257 IEA activation of JUN kinase activity
GO:0008022 IPI protein C-terminus binding
GO:0008023 IDA transcription elongation factor complex
GO:0008094 IDA DNA-dependent ATPase activity
GO:0008630 IEA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009411 IDA response to UV
GO:0009636 IEA response to toxic substance
GO:0010165 IEA response to X-ray
GO:0010224 IEA response to UV-B
GO:0010332 IEA response to gamma radiation
GO:0030296 IDA protein tyrosine kinase activator activity
GO:0032403 IDA protein complex binding
GO:0032784 IDA regulation of DNA-templated transcription, elongation
GO:0032786 IDA positive regulation of DNA-templated transcription, elongation
GO:0035264 IEA multicellular organism growth
GO:0045494 IEA photoreceptor cell maintenance
GO:0047485 IPI protein N-terminus binding
GO:0061098 IDA positive regulation of protein tyrosine kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000066807 Ercc6-201 protein_coding Mus_musculus 0 3856
ENSMUST00000067925 Hmgb2-201 protein_coding Mus_musculus 0.0001 55

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