C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interleukin 10 receptor, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000243646 IL10RB 9606 + 21:33266358-33297234 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000290200 IL10RB-001 33266358-33297234 protein_coding
  ENST00000422891 IL10RB-003 33266382-33296239 nonsense_mediated_decay
  ENST00000451065 IL10RB-004 33276612-33296350 nonsense_mediated_decay
  ENST00000493295 IL10RB-002 33267928-33296953 retained_intron
  ENST00000498371 IL10RB-005 33268282-33288120 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000290200ENST00000451065ENST00000493295
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000290200 11.088±0.00 16.084±0.00 1.499±1.01 6.776±4.22 10.969±0.00 3.383±0.00 6.058±4.21 4.899±3.27 7.803±6.44 3.780±0.00 10.390±6.08 48.582±26.94 8.798±0.00
ENST00000451065 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 16.840±0.00 34.655±0.00 2.409±0.00
ENST00000493295 N/A N/A N/A N/A 1.184±0.00 N/A N/A N/A 1.844±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007UY CIL_0007UY_0001 VISTA 21:32793653-33396760
CIL_0003TF CIL_0003TF_0001 CGP 21:33229901-33283212
CIL_0000MI CIL_0000MI_0002 CGP 21:33246774-33297234
CIL_0007I0 CIL_0007I0_0001 CGP 21:33266358-33359862

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004872 TAS receptor activity
GO:0004920 TAS interleukin-10 receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006954 TAS inflammatory response
GO:0006955 TAS immune response
GO:0007165 TAS signal transduction
GO:0016021 TAS integral component of membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0032002 NAS interleukin-28 receptor complex
GO:0051607 IEA defense response to virus
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068711 crfb4 cytokine receptor family member b4 protein_coding Danio_rerio
ENSDARG00000075776 crfb15 cytokine receptor family member B15 protein_coding Danio_rerio
ENSDARG00000096495 crfb15 cytokine receptor family member B15 protein_coding Danio_rerio
ENSMUSG00000022969 Il10rb interleukin 10 receptor, beta protein_coding Mus_musculus
ENSMUSG00000093701 Gm21970 predicted gene 21970 protein_coding Mus_musculus

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