C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polymerase (DNA directed), gamma 2, accessory subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000256525 POLG2 9606 - 17:64477785-64497036 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000539111 POLG2-001 64477785-64497036 protein_coding
  ENST00000577506 POLG2-007 64480289-64490969 processed_transcript
  ENST00000578687 POLG2-005 64486989-64492910 processed_transcript
  ENST00000578997 POLG2-003 64490862-64496755 nonsense_mediated_decay
  ENST00000580490 POLG2-010 64480348-64484230 processed_transcript
  ENST00000580893 POLG2-004 64490469-64493021 processed_transcript
  ENST00000581355 POLG2-006 64477787-64492720 protein_coding
  ENST00000582501 POLG2-008 64477964-64487474 processed_transcript
  ENST00000585104 POLG2-009 64481324-64485794 processed_transcript
  ENST00000585141 POLG2-002 64485158-64497019 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000539111ENST00000577506ENST00000578687ENST00000580490ENST00000581355ENST00000582501ENST00000585141
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000539111 1.647±0.00 1.501±0.00 N/A 0.407±0.00 1.866±0.00 N/A 1.318±0.00 N/A 0.419±0.16 N/A 1.449±0.00 4.184±1.76 0.789±0.06 12.249±6.39
ENST00000577506 N/A N/A N/A N/A N/A N/A 1.188±0.00 N/A 0.587±0.00 0.923±0.00 N/A N/A N/A N/A
ENST00000578687 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.665±0.00 N/A N/A N/A
ENST00000580490 N/A 4.656±0.00 N/A N/A N/A 1.122±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000581355 N/A N/A N/A N/A N/A N/A N/A 1.183±0.00 N/A N/A N/A 1.776±0.00 N/A N/A
ENST00000582501 N/A 2.315±0.00 N/A N/A 0.812±0.00 0.258±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000585141 0.498±0.00 2.110±0.00 0.330±0.00 N/A N/A 0.214±0.00 N/A 0.613±0.00 0.884±0.00 N/A N/A 1.312±0.00 0.292±0.04 1.303±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006GT CIL_0006GT_0001 CGP 17:64449037-64497036
CIL_00012I CIL_00012I_0001 CGP 17:64477785-64508199

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000262 TAS mitochondrial chromosome
GO:0003677 IEA DNA binding
GO:0003887 IEA DNA-directed DNA polymerase activity
GO:0005515 IPI protein binding
GO:0005739 IEA mitochondrion
GO:0006260 IEA:NAS DNA replication
GO:0006261 TAS DNA-dependent DNA replication
GO:0006281 IEA:NAS DNA repair
GO:0042645 IDA mitochondrial nucleoid
GO:0042802 IEA identical protein binding
GO:0070062 IDA extracellular vesicular exosome
GO:0071897 IEA DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074933 polg2 polymerase (DNA directed), gamma 2, accessory subunit protein_coding Danio_rerio
ENSMUSG00000020718 Polg2 polymerase (DNA directed), gamma 2, accessory subunit protein_coding Mus_musculus

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