C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polymerase (DNA directed), gamma 2, accessory subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020718 Polg2 10090 - 11:106768253-106779537 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021060 Polg2-001 106768253-106779515 protein_coding
  ENSMUST00000126201 Polg2-002 106775515-106779502 nonsense_mediated_decay
  ENSMUST00000127061 Polg2-004 106768253-106779537 nonsense_mediated_decay
  ENSMUST00000134029 Polg2-005 106771044-106779473 nonsense_mediated_decay
  ENSMUST00000142590 Polg2-006 106772642-106773850 retained_intron
  ENSMUST00000155107 Polg2-003 106768733-106779473 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021060ENSMUST00000126201ENSMUST00000127061ENSMUST00000134029ENSMUST00000155107
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021060 1.409±0.26 N/A 2.308±0.60 1.014±0.43 1.548±0.43 3.671±2.05 0.883±0.32 1.638±0.80 1.740±0.70 1.885±0.00 0.976±0.33 2.263±0.37 1.266±0.12 0.815±0.15
ENSMUST00000126201 N/A 3.781±0.89 N/A N/A N/A 3.300±1.39 N/A N/A N/A N/A N/A 2.651±0.03 N/A N/A
ENSMUST00000127061 1.186±0.00 2.624±1.12 N/A 0.811±0.10 2.869±1.52 3.711±0.00 N/A 1.172±0.52 0.780±0.15 1.352±0.34 0.367±0.09 2.465±1.12 0.726±0.05 0.544±0.00
ENSMUST00000134029 0.617±0.00 0.786±0.05 1.214±0.00 0.765±0.44 1.957±0.71 1.858±0.52 0.593±0.06 1.011±0.32 1.101±0.46 1.881±0.15 0.266±0.11 1.703±0.31 0.704±0.27 0.624±0.32
ENSMUST00000155107 0.860±0.18 N/A 1.162±0.00 0.569±0.25 1.838±0.00 N/A N/A 0.694±0.00 0.971±0.36 1.097±0.00 0.195±0.00 1.355±0.15 0.598±0.07 0.335±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00012N CIL_00012N_0002 CGP 11:106654217-106768794
CIL_0006GT CIL_0006GT_0002 CGP 11:106751226-106779537
CIL_00012I CIL_00012I_0002 CGP 11:106768253-106789185

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003887 IDA DNA-directed DNA polymerase activity
GO:0005515 IEA protein binding
GO:0005739 IDA mitochondrion
GO:0006260 IC DNA replication
GO:0006281 TAS DNA repair
GO:0042645 IEA mitochondrial nucleoid
GO:0042802 IPI identical protein binding
GO:0070062 IEA extracellular vesicular exosome
GO:0071897 IEA DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074933 polg2 polymerase (DNA directed), gamma 2, accessory subunit protein_coding Danio_rerio
ENSG00000256525 POLG2 polymerase (DNA directed), gamma 2, accessory subunit protein_coding Homo_sapiens

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