C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: peroxisome proliferator activated receptor gamma
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000000440 Pparg 10090 + 6:115361221-115490401 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000450 Pparg-201 115422066-115490401 protein_coding
  ENSMUST00000171644 Pparg-202 115361221-115490401 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000000450ENSMUST00000171644
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000000450 99.169±43.34 20.220±5.88 9.679±2.80 N/A 84.514±4.37 10.073±2.30 3.651±1.48 5.713±0.58 0.581±0.13 7.790±0.96 0.497±0.17 18.623±5.66 4.726±0.00 0.300±0.10
ENSMUST00000171644 N/A N/A 18.459±1.67 0.183±0.15 N/A 6.444±2.33 1.637±0.69 0.946±0.15 1.844±1.37 1.346±0.21 0.611±0.33 6.070±4.71 59.644±23.47 0.570±0.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001ZK CIL_0001ZK_0002 CGP 6:115245616-115490401
CIL_0004K9 CIL_0004K9_0002 CGP 6:115361221-115578350

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001012 IDA RNA polymerase II regulatory region DNA binding
GO:0001228 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001890 IMP placenta development
GO:0002674 IEA negative regulation of acute inflammatory response
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 TAS ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005829 IDA cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006954 TAS inflammatory response
GO:0007165 IEA signal transduction
GO:0007507 IEA heart development
GO:0008134 IEA transcription factor binding
GO:0008144 IEA drug binding
GO:0008217 IEA regulation of blood pressure
GO:0008270 IEA zinc ion binding
GO:0008285 IMP negative regulation of cell proliferation
GO:0009409 IEA response to cold
GO:0009612 IEA response to mechanical stimulus
GO:0010033 IEA response to organic substance
GO:0010871 IEA negative regulation of receptor biosynthetic process
GO:0010887 IEA negative regulation of cholesterol storage
GO:0010891 IEA negative regulation of sequestering of triglyceride
GO:0014070 IEA response to organic cyclic compound
GO:0015909 IMP long-chain fatty acid transport
GO:0019216 IEA regulation of lipid metabolic process
GO:0019395 IEA fatty acid oxidation
GO:0019899 IEA enzyme binding
GO:0019903 IEA protein phosphatase binding
GO:0030224 IEA monocyte differentiation
GO:0030308 IEA negative regulation of cell growth
GO:0030331 IEA estrogen receptor binding
GO:0030374 IEA ligand-dependent nuclear receptor transcription coactivator activity
GO:0030855 IGI epithelial cell differentiation
GO:0031000 IEA response to caffeine
GO:0031100 IEA organ regeneration
GO:0032526 IEA response to retinoic acid
GO:0032869 IEA cellular response to insulin stimulus
GO:0032966 IEA negative regulation of collagen biosynthetic process
GO:0033189 IEA response to vitamin A
GO:0033613 IEA activating transcription factor binding
GO:0033993 IEA response to lipid
GO:0035357 IEA peroxisome proliferator activated receptor signaling pathway
GO:0035902 IEA response to immobilization stress
GO:0036270 IEA response to diuretic
GO:0042493 IEA response to drug
GO:0042593 IEA glucose homeostasis
GO:0042594 IEA response to starvation
GO:0042953 IEA lipoprotein transport
GO:0043065 IEA positive regulation of apoptotic process
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0043627 IEA response to estrogen
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045165 IGI cell fate commitment
GO:0045444 IDA fat cell differentiation
GO:0045598 IDA regulation of fat cell differentiation
GO:0045600 IDA positive regulation of fat cell differentiation
GO:0045713 IEA low-density lipoprotein particle receptor biosynthetic process
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046321 IEA positive regulation of fatty acid oxidation
GO:0046965 IEA retinoid X receptor binding
GO:0048469 IEA cell maturation
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048662 IEA negative regulation of smooth muscle cell proliferation
GO:0048714 IEA positive regulation of oligodendrocyte differentiation
GO:0050872 IDA white fat cell differentiation
GO:0050873 IDA brown fat cell differentiation
GO:0051091 IEA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051974 IEA negative regulation of telomerase activity
GO:0055098 IEA response to low-density lipoprotein particle
GO:0060100 IEA positive regulation of phagocytosis, engulfment
GO:0060336 IEA negative regulation of interferon-gamma-mediated signaling pathway
GO:0071285 IDA cellular response to lithium ion
GO:0071300 IEA cellular response to retinoic acid
GO:0071306 IEA cellular response to vitamin E
GO:0071379 IEA cellular response to prostaglandin stimulus
GO:0071380 IEA cellular response to prostaglandin E stimulus
GO:0071407 IDA cellular response to organic cyclic compound
GO:0071455 IEA cellular response to hyperoxia
GO:1901558 IEA response to metformin
GO:2000230 IEA negative regulation of pancreatic stellate cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031848 pparg peroxisome proliferator activated receptor gamma protein_coding Danio_rerio
ENSG00000132170 PPARG peroxisome proliferator-activated receptor gamma protein_coding Homo_sapiens

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