C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear factor I/X
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000001911 Nfix 10090 - 8:84699876-84800344 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000076715 Nfix-003 84708614-84800140 protein_coding
  ENSMUST00000099070 Nfix-002 84708616-84800344 protein_coding
  ENSMUST00000109762 Nfix-004 84708626-84774369 protein_coding
  ENSMUST00000109764 Nfix-001 84704712-84773396 protein_coding
  ENSMUST00000126806 Nfix-005 84713795-84800024 protein_coding
  ENSMUST00000132236 Nfix-006 84708634-84714068 retained_intron
  ENSMUST00000148644 Nfix-008 84699876-84708218 processed_transcript
  ENSMUST00000148746 Nfix-007 84704712-84707716 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000076715ENSMUST00000099070ENSMUST00000109764ENSMUST00000126806
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000076715 18.773±0.00 N/A N/A N/A 5.255±0.00 5.932±1.12 N/A N/A 5.672±0.88 N/A 34.936±7.87 12.524±2.01 N/A 0.513±0.00
ENSMUST00000099070 N/A N/A N/A N/A N/A N/A 8.089±0.00 N/A N/A N/A N/A N/A N/A 1.021±0.00
ENSMUST00000109764 9.835±3.24 7.359±3.25 10.368±2.51 11.328±3.68 10.025±6.08 7.323±0.93 3.633±0.00 1.679±0.71 3.013±2.31 12.140±4.93 11.087±5.17 8.092±2.50 0.321±0.13 0.446±0.08
ENSMUST00000126806 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.680±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZV CIL_0007ZV_0002 VISTA 8:84428902-85032705
CIL_0007VV CIL_0007VV_0002 VISTA 8:84441926-85045230
CIL_0004F9 CIL_0004F9_0002 CGP 8:84699876-84800344

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228 IDA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006260 IEA DNA replication
GO:0006351 IEA transcription, DNA-templated
GO:0021549 IMP cerebellum development
GO:0021680 IMP cerebellar Purkinje cell layer development
GO:0021707 IMP cerebellar granule cell differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048708 IMP astrocyte differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043226 nfixa nuclear factor I/Xa protein_coding Danio_rerio
ENSDARG00000061836 nfixb nuclear factor I/Xb protein_coding Danio_rerio
ENSG00000008441 NFIX nuclear factor I/X (CCAAT-binding transcription factor) protein_coding Homo_sapiens

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