C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: kelch-like 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000014164 Klhl3 10090 - 13:58004221-58113592 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000091583 Klhl3-201 58004957-58102428 protein_coding
  ENSMUST00000160860 Klhl3-001 58004221-58113592 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000091583ENSMUST00000160860
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000091583 N/A 0.461±0.12 0.316±0.05 0.179±0.01 0.443±0.10 N/A 0.593±0.36 N/A 0.071±0.00 1.306±0.47 N/A 1.483±0.19
ENSMUST00000160860 0.291±0.04 0.321±0.16 0.580±0.17 0.322±0.16 0.714±0.18 1.451±0.23 0.250±0.00 0.527±0.35 0.160±0.08 1.137±0.43 0.111±0.03 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005P1 CIL_0005P1_0002 CGP 13:57421195-58113592
CIL_0005OY CIL_0005OY_0002 CGP 13:58004221-58128556

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0003779 IEA actin binding
GO:0003824 IEA catalytic activity
GO:0005829 ISS cytosol
GO:0005856 IEA cytoskeleton
GO:0016567 ISS protein ubiquitination
GO:0031463 ISS Cul3-RING ubiquitin ligase complex
GO:0042787 ISS protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0050801 ISS ion homeostasis
GO:0070294 ISS renal sodium ion absorption
GO:0070936 ISS protein K48-linked ubiquitination
GO:0072156 ISS distal tubule morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056647 KLHL3 Kelch-like protein 3 protein_coding Danio_rerio
ENSG00000146021 KLHL3 kelch-like family member 3 protein_coding Homo_sapiens

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