C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: c-mer proto-oncogene tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000014361 Mertk 10090 + 2:128698956-128802894 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000014505 Mertk-001 128698956-128802894 protein_coding
  ENSMUST00000140221 Mertk-002 128771313-128802678 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000014505ENSMUST00000140221
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000014505 2.843±0.84 2.831±0.34 1.441±0.16 1.049±1.00 1.721±0.46 1.061±0.00 0.725±0.40 5.064±1.86 1.658±0.65 5.457±2.31 0.215±0.05 4.443±1.65 5.476±3.24 0.236±0.03
ENSMUST00000140221 1.095±0.17 N/A 2.049±0.26 4.874±0.00 N/A 3.321±0.75 0.312±0.00 1.844±0.00 1.651±0.26 N/A 0.293±0.03 4.815±2.21 3.536±1.97 0.606±0.27

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00047R CIL_00047R_0002 CGP 2:128610104-128802894
CIL_00038G CIL_00038G_0003 CGP 2:128698956-128854261

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001750 IEA photoreceptor outer segment
GO:0001779 IGI natural killer cell differentiation
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0006909 IEA phagocytosis
GO:0007283 IGI spermatogenesis
GO:0016021 IEA integral component of membrane
GO:0016028 IEA rhabdomere
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030168 IMP platelet activation
GO:0032940 IMP secretion by cell
GO:0034446 IMP substrate adhesion-dependent cell spreading
GO:0043277 IMP apoptotic cell clearance
GO:0043491 IGI protein kinase B signaling
GO:0050766 IEA positive regulation of phagocytosis
GO:0051250 IGI negative regulation of lymphocyte activation
GO:0060041 IMP retina development in camera-type eye
GO:0060068 IGI vagina development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074695 mertk c-mer proto-oncogene tyrosine kinase protein_coding Danio_rerio
ENSG00000153208 MERTK MER proto-oncogene, tyrosine kinase protein_coding Homo_sapiens

Loading