C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP-binding cassette, sub-family A (ABC1), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000015243 Abca1 10090 - 4:53030787-53159895 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030010 Abca1-001 53030787-53159895 protein_coding
  ENSMUST00000149127 Abca1-002 53035488-53040926 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030010
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030010 20.903±1.15 23.649±7.41 5.598±1.09 2.543±0.72 14.138±2.48 1.425±0.41 1.819±0.68 4.501±0.87 3.769±1.93 7.618±0.90 1.184±0.23 22.211±6.57 7.658±6.34 3.458±1.82

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00022C CIL_00022C_0003 CGP 4:53030787-53622478

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002790 IMP peptide secretion
GO:0005102 IEA receptor binding
GO:0005515 IPI protein binding
GO:0005548 IDA phospholipid transporter activity
GO:0005794 IDA Golgi apparatus
GO:0005886 IDA plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0006497 IMP protein lipidation
GO:0006911 IMP phagocytosis, engulfment
GO:0007040 IEA lysosome organization
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007584 IEA response to nutrient
GO:0008203 IDA cholesterol metabolic process
GO:0008509 IDA anion transmembrane transporter activity
GO:0009897 IDA external side of plasma membrane
GO:0009986 IEA cell surface
GO:0010875 IMP positive regulation of cholesterol efflux
GO:0015914 IEA phospholipid transport
GO:0016197 IEA endosomal transport
GO:0016887 IEA ATPase activity
GO:0017127 IDA cholesterol transporter activity
GO:0019905 IEA syntaxin binding
GO:0030139 IEA endocytic vesicle
GO:0030301 IEA cholesterol transport
GO:0030819 IEA positive regulation of cAMP biosynthetic process
GO:0031267 IEA small GTPase binding
GO:0032367 IEA intracellular cholesterol transport
GO:0032489 IEA regulation of Cdc42 protein signal transduction
GO:0033344 IDA cholesterol efflux
GO:0033700 IDA phospholipid efflux
GO:0034185 IEA apolipoprotein binding
GO:0034186 IEA apolipoprotein A-I binding
GO:0034188 IEA apolipoprotein A-I receptor activity
GO:0034364 IEA high-density lipoprotein particle
GO:0034380 IEA high-density lipoprotein particle assembly
GO:0034616 IEA response to laminar fluid shear stress
GO:0038027 IEA apolipoprotein A-I-mediated signaling pathway
GO:0042157 IMP lipoprotein metabolic process
GO:0042158 IMP lipoprotein biosynthetic process
GO:0042493 IEA response to drug
GO:0042632 IEA cholesterol homeostasis
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0043691 IMP reverse cholesterol transport
GO:0045121 IEA membrane raft
GO:0045332 IMP phospholipid translocation
GO:0045335 IEA phagocytic vesicle
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050702 IEA interleukin-1 beta secretion
GO:0051117 IEA ATPase binding
GO:0055091 IEA phospholipid homeostasis
GO:0055098 IEA response to low-density lipoprotein particle
GO:0060155 IEA platelet dense granule organization
GO:0071222 IDA cellular response to lipopolysaccharide
GO:0071300 IDA cellular response to retinoic acid
GO:0071397 IEA cellular response to cholesterol

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074635 abca1a ATP-binding cassette, sub-family A (ABC1), member 1A protein_coding Danio_rerio
ENSDARG00000079009 abca1b ATP-binding cassette, sub-family A (ABC1), member 1B protein_coding Danio_rerio
ENSG00000165029 ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 protein_coding Homo_sapiens

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