C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: caseinolytic mitochondrial matrix peptidase chaperone subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000015357 Clpx 10090 + 9:65294260-65330658 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000015501 Clpx-001 65294260-65330657 protein_coding
  ENSMUST00000113824 Clpx-201 65294295-65330658 protein_coding
  ENSMUST00000147279 Clpx-003 65310152-65318737 protein_coding
  ENSMUST00000148632 Clpx-002 65294332-65309230 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000015501ENSMUST00000113824ENSMUST00000148632
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000015501 6.604±0.63 6.182±0.10 5.966±0.68 7.185±0.54 8.689±4.01 6.838±2.78 7.500±0.99 13.415±1.60 16.102±7.89 4.386±1.55 13.595±2.00 10.172±2.24 7.150±3.48 36.935±1.11
ENSMUST00000113824 3.309±0.90 22.780±4.86 2.501±0.00 3.855±2.50 10.168±2.07 4.440±1.26 4.916±0.89 4.665±1.15 13.537±9.42 1.955±0.68 N/A 6.163±3.93 12.020±7.25 19.269±0.00
ENSMUST00000148632 N/A 8.930±2.24 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RY CIL_0007RY_0002 VISTA 9:65081642-65684657

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004176 ISS ATP-dependent peptidase activity
GO:0005515 IPI protein binding
GO:0005524 IDA ATP binding
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0005759 ISS mitochondrial matrix
GO:0006200 ISS ATP catabolic process
GO:0006457 IEA protein folding
GO:0009368 ISS endopeptidase Clp complex
GO:0009841 IEA mitochondrial endopeptidase Clp complex
GO:0010952 IEA positive regulation of peptidase activity
GO:0016504 IEA peptidase activator activity
GO:0016887 IDA ATPase activity
GO:0042645 IEA mitochondrial nucleoid
GO:0046872 IEA metal ion binding
GO:0051082 IEA unfolded protein binding
GO:0051603 ISS proteolysis involved in cellular protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029063 clpxa ClpX caseinolytic peptidase X homolog a protein_coding Danio_rerio
ENSDARG00000067796 clpxb caseinolytic peptidase X homolog b protein_coding Danio_rerio
ENSDARG00000086455 CLPX (3 of 3) caseinolytic mitochondrial matrix peptidase chaperone subunit protein_coding Danio_rerio
ENSG00000166855 CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit protein_coding Homo_sapiens

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