C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sequestosome 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000015837 Sqstm1 10090 - 11:50199366-50210827 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000015981 Sqstm1-002 50199366-50210791 protein_coding
  ENSMUST00000102774 Sqstm1-001 50200152-50210827 protein_coding
  ENSMUST00000131214 Sqstm1-007 50202312-50206100 retained_intron
  ENSMUST00000136936 Sqstm1-005 50200167-50202954 protein_coding
  ENSMUST00000143379 Sqstm1-004 50200611-50210765 protein_coding
  ENSMUST00000147846 Sqstm1-003 50202443-50203118 retained_intron
  ENSMUST00000154805 Sqstm1-006 50205679-50207319 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000015981ENSMUST00000102774ENSMUST00000136936ENSMUST00000147846
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000015981 12.439±0.06 N/A N/A 10.325±1.69 5.324±0.00 18.811±0.00 N/A 21.394±1.50 11.057±5.96 14.737±0.00 N/A 24.129±8.09 17.824±0.00 7.338±2.35
ENSMUST00000102774 32.655±6.20 212.433±89.60 128.187±30.23 72.523±16.20 30.898±7.55 62.197±38.01 37.732±7.08 56.205±9.90 50.724±9.07 77.125±39.68 198.764±35.11 132.880±56.37 197.198±102.24 12.295±2.93
ENSMUST00000136936 N/A N/A N/A 58.527±0.00 35.032±0.00 N/A N/A N/A N/A N/A N/A 99.945±6.47 105.197±25.67 9.411±0.00
ENSMUST00000147846 N/A N/A N/A 202.907±0.00 N/A N/A N/A N/A N/A N/A N/A 282.704±0.00 207.879±69.61 66.235±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000407 IDA pre-autophagosomal structure
GO:0000932 ISS cytoplasmic mRNA processing body
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0002376 IEA immune system process
GO:0003712 TAS transcription cofactor activity
GO:0005080 ISS protein kinase C binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005764 IEA lysosome
GO:0005768 IEA endosome
GO:0005776 ISS autophagic vacuole
GO:0005783 IEA endoplasmic reticulum
GO:0006914 ISS autophagy
GO:0006915 IEA apoptotic process
GO:0008270 IEA zinc ion binding
GO:0016234 IEA inclusion body
GO:0016235 IDA aggresome
GO:0016236 ISS macroautophagy
GO:0016239 IEA positive regulation of macroautophagy
GO:0016605 IEA PML body
GO:0019901 IEA protein kinase binding
GO:0030154 IEA cell differentiation
GO:0031410 IEA cytoplasmic vesicle
GO:0042169 ISS SH2 domain binding
GO:0042802 IDA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0043122 ISS regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043130 ISS ubiquitin binding
GO:0051291 IEA protein heterooligomerization
GO:0070062 IEA extracellular vesicular exosome
GO:0070530 IDA K63-linked polyubiquitin binding
GO:2001141 TAS regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075014 sqstm1 sequestosome 1 protein_coding Danio_rerio
ENSG00000161011 SQSTM1 sequestosome 1 protein_coding Homo_sapiens

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