C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: retinoid X receptor alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000015846 Rxra 10090 + 2:27676440-27762957 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000077257 Rxra-001 27677201-27762957 protein_coding
  ENSMUST00000100251 Rxra-002 27709292-27760183 protein_coding
  ENSMUST00000113934 Rxra-003 27710583-27760183 protein_coding
  ENSMUST00000129514 Rxra-004 27676440-27741898 protein_coding
  ENSMUST00000148756 Rxra-005 27740201-27748671 processed_transcript
  ENSMUST00000166775 Rxra-201 27677262-27761417 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000077257ENSMUST00000100251ENSMUST00000113934ENSMUST00000129514ENSMUST00000166775
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000077257 31.737±12.64 18.099±1.93 30.459±0.24 3.064±1.68 27.828±9.75 21.374±2.64 7.553±3.56 19.593±7.49 38.352±37.81 20.647±7.10 23.476±7.65 16.044±2.57 26.921±18.30 2.662±0.21
ENSMUST00000100251 14.020±0.00 N/A N/A 3.979±1.68 N/A 6.210±0.00 N/A 12.273±0.00 19.345±16.40 18.313±0.63 N/A 11.320±3.39 25.982±17.88 6.065±1.47
ENSMUST00000113934 8.284±0.00 15.437±3.21 N/A N/A 26.439±7.06 15.960±4.42 N/A 11.747±1.94 N/A N/A N/A 17.240±4.39 N/A 13.086±3.01
ENSMUST00000129514 N/A 25.007±3.87 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000166775 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.206±0.80 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000151 CIL_000151_0002 CGP 2:27515157-27762957
CIL_000152 CIL_000152_0002 CGP 2:27676440-28039514

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IEA nuclear chromatin
GO:0000977 IEA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001701 IGI in utero embryonic development
GO:0001890 IMP placenta development
GO:0001893 IGI maternal placenta development
GO:0003007 TAS heart morphogenesis
GO:0003677 IDA DNA binding
GO:0003700 IGI sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 IDA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0004886 IDA 9-cis retinoic acid receptor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IGI regulation of transcription from RNA polymerase II promoter
GO:0007507 IMP:TAS heart development
GO:0007566 IGI embryo implantation
GO:0008134 IPI transcription factor binding
GO:0008270 IEA zinc ion binding
GO:0010629 TAS negative regulation of gene expression
GO:0019048 IEA modulation by virus of host morphology or physiology
GO:0019899 IEA enzyme binding
GO:0031490 IDA chromatin DNA binding
GO:0032526 IEA response to retinoic acid
GO:0035357 IEA peroxisome proliferator activated receptor signaling pathway
GO:0042809 IEA vitamin D receptor binding
GO:0043010 IGI camera-type eye development
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IGI sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044323 IEA retinoic acid-responsive element binding
GO:0045893 IGI:TAS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0045994 IGI positive regulation of translational initiation by iron
GO:0046982 IEA protein heterodimerization activity
GO:0048384 IDA retinoic acid receptor signaling pathway
GO:0051289 IEA protein homotetramerization
GO:0055007 TAS cardiac muscle cell differentiation
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0055012 IGI ventricular cardiac muscle cell differentiation
GO:0060038 IGI:TAS cardiac muscle cell proliferation
GO:0060485 TAS mesenchyme development
GO:0060528 IMP secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
GO:0060687 IMP regulation of branching involved in prostate gland morphogenesis
GO:0060978 TAS angiogenesis involved in coronary vascular morphogenesis
GO:0061032 TAS visceral serous pericardium development
GO:0070644 IEA vitamin D response element binding
GO:1901522 IDA positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000186350 RXRA retinoid X receptor, alpha protein_coding Homo_sapiens

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