C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium channel, voltage-dependent, beta 4 subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000017412 Cacnb4 10090 - 2:52428320-52676831 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000078324 Cacnb4-002 52428325-52676831 protein_coding
  ENSMUST00000102760 Cacnb4-001 52428325-52558560 protein_coding
  ENSMUST00000102761 Cacnb4-003 52428325-52558567 protein_coding
  ENSMUST00000132322 Cacnb4-004 52556187-52556709 processed_transcript
  ENSMUST00000148837 Cacnb4-005 52675727-52676143 processed_transcript
  ENSMUST00000178799 Cacnb4-201 52428320-52676582 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000078324ENSMUST00000102760ENSMUST00000102761ENSMUST00000148837ENSMUST00000178799
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000078324 0.056±0.01 N/A N/A N/A N/A N/A N/A 0.318±0.03 0.058±0.00 N/A N/A 0.330±0.00 N/A 0.065±0.01
ENSMUST00000102760 0.198±0.17 0.106±0.04 0.124±0.00 2.745±0.44 0.220±0.11 0.124±0.01 0.077±0.04 0.182±0.00 0.169±0.05 0.198±0.00 N/A 0.094±0.02 0.059±0.04 0.135±0.02
ENSMUST00000102761 0.100±0.00 N/A N/A 1.577±0.45 0.241±0.00 0.121±0.03 N/A N/A 0.046±0.01 N/A 0.073±0.00 0.288±0.15 0.032±0.00 0.098±0.02
ENSMUST00000148837 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 18.635±15.53 N/A N/A
ENSMUST00000178799 0.161±0.09 0.109±0.03 0.328±0.22 1.099±0.55 0.083±0.01 0.077±0.01 N/A 0.420±0.00 0.084±0.03 N/A 0.092±0.03 0.357±0.17 0.061±0.04 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007E4 CIL_0007E4_0002 CGP 2:52397951-52676831
CIL_0007E3 CIL_0007E3_0002 CGP 2:52428320-52742281

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005245 IMP voltage-gated calcium channel activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005891 IDA voltage-gated calcium channel complex
GO:0006816 IMP calcium ion transport
GO:0006874 IMP cellular calcium ion homeostasis
GO:0007214 IMP gamma-aminobutyric acid signaling pathway
GO:0007528 IMP neuromuscular junction development
GO:0007628 IMP adult walking behavior
GO:0008331 TAS high voltage-gated calcium channel activity
GO:0014051 IMP gamma-aminobutyric acid secretion
GO:0019227 IMP neuronal action potential propagation
GO:0019901 IEA protein kinase binding
GO:0035249 IMP synaptic transmission, glutamatergic
GO:0042391 IMP regulation of membrane potential
GO:0045202 IEA synapse
GO:0046058 IMP cAMP metabolic process
GO:0048536 IMP spleen development
GO:0048538 IMP thymus development
GO:0048541 IMP Peyer's patch development
GO:0048747 IMP muscle fiber development
GO:0050852 IMP T cell receptor signaling pathway
GO:0050877 IMP neurological system process
GO:0050908 IMP detection of light stimulus involved in visual perception
GO:0070588 IEA calcium ion transmembrane transport
GO:1901385 IEA regulation of voltage-gated calcium channel activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009738 cacnb4a calcium channel, voltage-dependent, beta 4a subunit protein_coding Danio_rerio
ENSDARG00000062174 cacnb4b calcium channel, voltage-dependent, beta 4b subunit protein_coding Danio_rerio
ENSG00000182389 CACNB4 calcium channel, voltage-dependent, beta 4 subunit protein_coding Homo_sapiens

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