C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcium channel, voltage-dependent, beta 4 subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000182389 CACNB4 9606 - 2:151832776-152099079 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000201943 CACNB4-004 151839114-152099023 protein_coding
  ENST00000360283 CACNB4-201 151838927-151973935 protein_coding
  ENST00000397327 CACNB4-002 151838684-151973940 protein_coding
  ENST00000427385 CACNB4-005 151838814-152098721 protein_coding
  ENST00000434468 CACNB4-009 151876480-151971988 protein_coding
  ENST00000439467 CACNB4-006 151838614-152098461 protein_coding
  ENST00000470066 CACNB4-007 151865761-151973720 retained_intron
  ENST00000475848 CACNB4-008 151883297-151973971 processed_transcript
  ENST00000534999 CACNB4-003 151838626-151973940 protein_coding
  ENST00000539935 CACNB4-001 151832776-152099079 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000201943ENST00000427385ENST00000439467ENST00000470066ENST00000475848ENST00000539935
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000201943 N/A N/A N/A N/A N/A N/A N/A 0.030±0.00 N/A N/A N/A N/A 0.126±0.00 N/A
ENST00000427385 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.063±0.00 N/A N/A N/A
ENST00000439467 N/A N/A N/A N/A N/A N/A 0.124±0.00 N/A N/A N/A N/A 0.154±0.00 0.080±0.00 N/A
ENST00000470066 0.026±0.00 0.051±0.00 0.207±0.00 N/A 0.118±0.04 N/A 0.018±0.00 N/A 0.019±0.00 0.213±0.14 N/A 0.064±0.00 0.021±0.00 N/A
ENST00000475848 N/A N/A N/A N/A N/A 0.742±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000539935 0.026±0.00 N/A N/A 3.611±1.49 0.089±0.00 N/A N/A 0.608±0.00 0.007±0.00 N/A N/A 0.047±0.00 0.030±0.00 0.381±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007E4 CIL_0007E4_0001 CGP 2:151788984-152099079
CIL_0007E3 CIL_0007E3_0001 CGP 2:151832776-152175992

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005245 IDA:IEA voltage-gated calcium channel activity
GO:0005515 IPI:IEA protein binding
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005891 IDA:IEA voltage-gated calcium channel complex
GO:0006810 TAS transport
GO:0006816 IEA calcium ion transport
GO:0006874 IEA cellular calcium ion homeostasis
GO:0007214 IEA gamma-aminobutyric acid signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0007528 IEA neuromuscular junction development
GO:0007628 IEA adult walking behavior
GO:0008331 IDA high voltage-gated calcium channel activity
GO:0009898 TAS cytoplasmic side of plasma membrane
GO:0014051 IEA gamma-aminobutyric acid secretion
GO:0019227 IEA neuronal action potential propagation
GO:0019901 IEA protein kinase binding
GO:0035249 IEA synaptic transmission, glutamatergic
GO:0042391 IEA regulation of membrane potential
GO:0045202 IDA synapse
GO:0046058 IEA cAMP metabolic process
GO:0048536 IEA spleen development
GO:0048538 IEA thymus development
GO:0048541 IEA Peyer's patch development
GO:0048747 IEA muscle fiber development
GO:0050852 IEA T cell receptor signaling pathway
GO:0050877 IEA neurological system process
GO:0050908 IEA detection of light stimulus involved in visual perception
GO:0051899 TAS membrane depolarization
GO:0070588 IEA calcium ion transmembrane transport
GO:1901385 IMP regulation of voltage-gated calcium channel activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009738 cacnb4a calcium channel, voltage-dependent, beta 4a subunit protein_coding Danio_rerio
ENSDARG00000062174 cacnb4b calcium channel, voltage-dependent, beta 4b subunit protein_coding Danio_rerio
ENSMUSG00000017412 Cacnb4 calcium channel, voltage-dependent, beta 4 subunit protein_coding Mus_musculus

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