C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Der1-like domain family, member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018442 Derl2 10090 - 11:71007164-71019841 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018586 Derl2-005 71010351-71019269 nonsense_mediated_decay
  ENSMUST00000108523 Derl2-002 71007164-71019242 protein_coding
  ENSMUST00000131340 Derl2-004 71014566-71019212 nonsense_mediated_decay
  ENSMUST00000132198 Derl2-006 71013122-71019275 nonsense_mediated_decay
  ENSMUST00000140712 Derl2-003 71012122-71019243 retained_intron
  ENSMUST00000143850 Derl2-001 71007442-71019303 protein_coding
  ENSMUST00000171041 Derl2-007 71009933-71019841 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018586ENSMUST00000108523ENSMUST00000132198ENSMUST00000140712ENSMUST00000143850ENSMUST00000171041
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018586 N/A 9.469±0.56 N/A N/A N/A 8.145±0.00 N/A N/A 28.460±5.02 N/A N/A N/A N/A 16.159±1.54
ENSMUST00000108523 N/A 6.469±1.52 N/A N/A N/A N/A 5.874±0.00 N/A 21.437±4.42 N/A N/A N/A N/A N/A
ENSMUST00000132198 N/A N/A N/A N/A 12.387±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000140712 1.316±0.23 1.412±0.28 N/A N/A 1.111±0.17 1.293±0.10 N/A N/A 3.822±0.13 2.064±0.31 N/A 0.983±0.09 N/A N/A
ENSMUST00000143850 3.724±0.44 4.314±1.69 8.455±1.01 7.615±4.56 2.717±0.95 3.331±0.76 2.554±0.51 5.404±1.04 10.949±2.51 4.896±1.27 2.198±0.27 3.785±2.59 7.691±3.21 3.188±0.34
ENSMUST00000171041 4.838±0.99 N/A N/A 4.167±0.00 3.222±0.00 N/A 4.095±0.88 4.305±0.38 8.927±2.01 N/A 2.655±0.55 11.784±1.59 19.502±7.87 10.747±2.66

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000FL CIL_0000FL_0002 CGP 11:70984091-71019841
CIL_0002PM CIL_0002PM_0002 CGP 11:71007164-71027371

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001967 IMP suckling behavior
GO:0003674 ND molecular_function
GO:0005515 IEA protein binding
GO:0005769 IDA early endosome
GO:0005770 IDA late endosome
GO:0005783 IDA endoplasmic reticulum
GO:0008284 ISS positive regulation of cell proliferation
GO:0016020 IEA membrane
GO:0030176 ISS integral component of endoplasmic reticulum membrane
GO:0030307 ISS positive regulation of cell growth
GO:0030433 ISS ER-associated ubiquitin-dependent protein catabolic process
GO:0030968 ISS endoplasmic reticulum unfolded protein response
GO:0030970 IMP retrograde protein transport, ER to cytosol

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042401 derl2 Der1-like domain family, member 2 protein_coding Danio_rerio
ENSG00000072849 DERL2 derlin 2 protein_coding Homo_sapiens

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