C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: derlin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000072849 DERL2 9606 - 17:5471251-5486811 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000158771 DERL2-001 5471251-5486217 protein_coding
  ENST00000570848 DERL2-008 5474610-5486178 protein_coding
  ENST00000571476 DERL2-011 5474727-5486148 nonsense_mediated_decay
  ENST00000571968 DERL2-004 5482810-5486811 processed_transcript
  ENST00000571971 DERL2-009 5480071-5486178 protein_coding
  ENST00000572834 DERL2-010 5474452-5486162 protein_coding
  ENST00000573547 DERL2-013 5474309-5480273 retained_intron
  ENST00000573637 DERL2-002 5480400-5486165 nonsense_mediated_decay
  ENST00000574700 DERL2-005 5480510-5486183 retained_intron
  ENST00000574952 DERL2-003 5480124-5486276 nonsense_mediated_decay
  ENST00000575209 DERL2-006 5482270-5486175 retained_intron
  ENST00000575605 DERL2-012 5474610-5482879 protein_coding
  ENST00000576551 DERL2-007 5477897-5486159 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000158771ENST00000571476ENST00000571971ENST00000572834ENST00000573547
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000158771 2.617±0.00 4.120±0.00 0.783±0.00 2.153±0.85 3.333±0.00 1.445±0.02 0.696±0.42 3.528±1.76 1.792±0.22 1.492±0.12 0.952±0.01 3.080±1.49 1.813±0.29 5.438±0.00
ENST00000571476 N/A N/A N/A 6.513±0.00 N/A 8.728±0.00 4.401±0.00 7.514±0.00 N/A 10.094±0.00 5.616±0.00 9.131±0.00 N/A N/A
ENST00000571971 9.962±0.00 N/A 3.723±0.00 N/A N/A N/A N/A 4.408±0.00 N/A N/A N/A 20.090±0.00 26.839±0.00 117.805±0.00
ENST00000572834 N/A N/A N/A N/A N/A N/A N/A N/A 14.641±0.00 N/A 4.928±0.00 N/A N/A N/A
ENST00000573547 N/A N/A N/A N/A 8.827±0.00 6.179±0.00 5.223±0.00 26.972±0.00 14.340±0.00 9.942±0.00 3.315±0.00 11.822±0.00 14.366±3.56 24.060±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000FL CIL_0000FL_0001 CGP 17:5440912-5486811
CIL_0002PM CIL_0002PM_0001 CGP 17:5471251-5490814

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001967 IEA suckling behavior
GO:0005515 IPI protein binding
GO:0005769 IEA early endosome
GO:0005770 IEA late endosome
GO:0005783 IDA endoplasmic reticulum
GO:0008284 IDA positive regulation of cell proliferation
GO:0016020 IDA membrane
GO:0030176 IDA integral component of endoplasmic reticulum membrane
GO:0030307 IDA positive regulation of cell growth
GO:0030433 IMP ER-associated ubiquitin-dependent protein catabolic process
GO:0030968 IDA endoplasmic reticulum unfolded protein response
GO:0030970 IMP retrograde protein transport, ER to cytosol

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042401 derl2 Der1-like domain family, member 2 protein_coding Danio_rerio
ENSMUSG00000018442 Derl2 Der1-like domain family, member 2 protein_coding Mus_musculus

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