C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor co-repressor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018501 Ncor1 10090 - 11:62316426-62458541 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018645 Ncor1-001 62316426-62457332 protein_coding
  ENSMUST00000037575 Ncor1-201 62317797-62359791 protein_coding
  ENSMUST00000069456 Ncor1-010 62401383-62457323 protein_coding
  ENSMUST00000101066 Ncor1-202 62316426-62438515 protein_coding
  ENSMUST00000101067 Ncor1-004 62317797-62438481 protein_coding
  ENSMUST00000101068 Ncor1-008 62366944-62438515 retained_intron
  ENSMUST00000124027 Ncor1-011 62395186-62401550 retained_intron
  ENSMUST00000127471 Ncor1-009 62373386-62457806 protein_coding
  ENSMUST00000131911 Ncor1-006 62325262-62330044 retained_intron
  ENSMUST00000141447 Ncor1-012 62419730-62458541 protein_coding
  ENSMUST00000151498 Ncor1-019 62344785-62392659 protein_coding
  ENSMUST00000155486 Ncor1-007 62384757-62438515 protein_coding
  ENSMUST00000155712 Ncor1-003 62316690-62378517 protein_coding
  ENSMUST00000156740 Ncor1-013 62317797-62359015 protein_coding
  ENSMUST00000159069 Ncor1-002 62344785-62392659 protein_coding
  ENSMUST00000159224 Ncor1-021 62343021-62351390 protein_coding
  ENSMUST00000159315 Ncor1-025 62317601-62321221 protein_coding
  ENSMUST00000160171 Ncor1-014 62392049-62395192 retained_intron
  ENSMUST00000161116 Ncor1-020 62353906-62369301 protein_coding
  ENSMUST00000161281 Ncor1-024 62327131-62330943 retained_intron
  ENSMUST00000161288 Ncor1-017 62373319-62383205 protein_coding
  ENSMUST00000161432 Ncor1-022 62340455-62344901 retained_intron
  ENSMUST00000161699 Ncor1-015 62373364-62384843 protein_coding
  ENSMUST00000161767 Ncor1-023 62325512-62330168 retained_intron
  ENSMUST00000162077 Ncor1-016 62376616-62383263 retained_intron
  ENSMUST00000162236 Ncor1-018 62373384-62383354 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018645ENSMUST00000037575ENSMUST00000101066ENSMUST00000101067ENSMUST00000127471ENSMUST00000151498ENSMUST00000155486ENSMUST00000155712ENSMUST00000156740ENSMUST00000159069ENSMUST00000161699
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018645 5.549±0.09 6.892±1.25 N/A N/A 8.959±0.00 6.351±1.19 3.355±0.65 4.466±0.16 3.717±0.80 6.769±2.28 3.665±0.00 10.845±0.55 N/A 5.273±0.94
ENSMUST00000037575 N/A N/A N/A 18.060±0.00 N/A N/A N/A N/A 9.425±3.54 N/A N/A N/A 10.937±5.55 N/A
ENSMUST00000101066 N/A 7.969±0.00 6.462±0.00 7.974±2.01 6.857±0.00 N/A N/A N/A 3.380±0.00 N/A 4.814±0.39 12.690±2.98 5.892±2.21 N/A
ENSMUST00000101067 N/A N/A N/A 12.795±0.00 N/A N/A N/A N/A N/A N/A N/A 16.516±0.00 9.262±0.09 5.323±0.00
ENSMUST00000127471 N/A 20.509±1.02 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000151498 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.799±0.00
ENSMUST00000155486 N/A N/A N/A 42.722±0.00 N/A N/A N/A N/A N/A N/A N/A 39.708±0.00 29.501±2.58 22.341±0.00
ENSMUST00000155712 8.520±1.81 N/A 11.460±1.14 17.267±0.64 7.661±1.03 N/A 3.875±0.56 7.412±1.06 7.312±2.58 5.619±0.08 8.982±0.85 12.238±6.89 9.583±4.23 N/A
ENSMUST00000156740 13.923±1.87 18.226±3.27 10.588±1.24 15.212±0.00 17.769±3.13 15.015±2.88 7.118±1.71 10.830±1.72 8.090±2.33 13.264±5.46 N/A 19.711±6.50 N/A 11.301±3.31
ENSMUST00000159069 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 11.057±0.00
ENSMUST00000161699 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 89.230±0.00 N/A 50.215±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000H6 CIL_0000H6_0002 CGP 11:62267224-62328451
CIL_0000NU CIL_0000NU_0002 CGP 11:62281473-62458541
CIL_0006JO CIL_0006JO_0003 CGP 11:62316426-62514417

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000118 IEA histone deacetylase complex
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IEA nuclear chromatin
GO:0001102 IEA RNA polymerase II activating transcription factor binding
GO:0002361 IMP CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0003677 IDA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003714 IGI transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IPI transcription factor complex
GO:0005737 IDA cytoplasm
GO:0005876 IEA spindle microtubule
GO:0006357 IGI regulation of transcription from RNA polymerase II promoter
GO:0014067 IMP negative regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 IEA membrane
GO:0016580 IEA Sin3 complex
GO:0017053 IPI transcriptional repressor complex
GO:0021794 IMP thalamus development
GO:0031065 IDA positive regulation of histone deacetylation
GO:0032922 IGI circadian regulation of gene expression
GO:0035033 IMP histone deacetylase regulator activity
GO:0035257 IEA nuclear hormone receptor binding
GO:0040014 IGI regulation of multicellular organism growth
GO:0042632 IMP cholesterol homeostasis
GO:0042826 IEA histone deacetylase binding
GO:0042974 IDA retinoic acid receptor binding
GO:0043565 IDA sequence-specific DNA binding
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0046329 IEA negative regulation of JNK cascade
GO:0046965 IDA retinoid X receptor binding
GO:0046966 IPI thyroid hormone receptor binding
GO:0051225 IEA spindle assembly
GO:0060318 IMP definitive erythrocyte differentiation
GO:0072362 IEA regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter
GO:0072368 IEA regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035285 ncor1 nuclear receptor co-repressor 1 protein_coding Danio_rerio
ENSG00000141027 NCOR1 nuclear receptor corepressor 1 protein_coding Homo_sapiens

Loading