C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nuclear receptor co-repressor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000018645 Ncor1-001 ENSMUSG00000018501 10090 - 11:62316426-62457332 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLiverLungMuscleOvaryTestisENSMUST00000018645
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENSMUST00000018645 5.549±0.09 6.892±1.25 8.959±0.00 6.351±1.19 3.355±0.65 4.466±0.16 3.717±0.80 6.769±2.28 3.665±0.00 10.845±0.55 5.273±0.94

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000H6 CIL_0000H6_0002 CGP 11:62267224-62328451
CIL_0000NU CIL_0000NU_0002 CGP 11:62281473-62458541
CIL_0006JO CIL_0006JO_0003 CGP 11:62316426-62514417

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000118 IEA histone deacetylase complex
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IEA nuclear chromatin
GO:0001102 IEA RNA polymerase II activating transcription factor binding
GO:0002361 IMP CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0003677 IDA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003714 IGI transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IPI transcription factor complex
GO:0005737 IDA cytoplasm
GO:0005876 IEA spindle microtubule
GO:0006357 IGI regulation of transcription from RNA polymerase II promoter
GO:0014067 IMP negative regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 IEA membrane
GO:0016580 IEA Sin3 complex
GO:0017053 IPI transcriptional repressor complex
GO:0021794 IMP thalamus development
GO:0031065 IDA positive regulation of histone deacetylation
GO:0032922 IGI circadian regulation of gene expression
GO:0035033 IMP histone deacetylase regulator activity
GO:0035257 IEA nuclear hormone receptor binding
GO:0040014 IGI regulation of multicellular organism growth
GO:0042632 IMP cholesterol homeostasis
GO:0042826 IEA histone deacetylase binding
GO:0042974 IDA retinoic acid receptor binding
GO:0043565 IDA sequence-specific DNA binding
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0046329 IEA negative regulation of JNK cascade
GO:0046965 IDA retinoid X receptor binding
GO:0046966 IPI thyroid hormone receptor binding
GO:0051225 IEA spindle assembly
GO:0060318 IMP definitive erythrocyte differentiation
GO:0072362 IEA regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter
GO:0072368 IEA regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000268712 NCOR1-001 protein_coding Homo_sapiens 0 5910
ENST00000395848 NCOR1-007 protein_coding Homo_sapiens 0 3230
ENST00000395849 NCOR1-018 protein_coding Homo_sapiens 0 3764
ENST00000395851 NCOR1-003 protein_coding Homo_sapiens 0 6804
ENST00000395857 NCOR1-201 protein_coding Homo_sapiens 0 8462
ENST00000411510 NCOR1-009 protein_coding Homo_sapiens 0 2462
ENST00000430577 NCOR1-012 protein_coding Homo_sapiens 0 499
ENST00000436828 NCOR1-002 protein_coding Homo_sapiens 0 2180
ENST00000458113 NCOR1-022 retained_intron Homo_sapiens 0 4063
ENST00000460276 NCOR1-008 nonsense_mediated_decay Homo_sapiens 0 2294
ENST00000464381 NCOR1-010 retained_intron Homo_sapiens 0 1402
ENST00000470782 NCOR1-005 retained_intron Homo_sapiens 0 3363
ENST00000472189 NCOR1-013 retained_intron Homo_sapiens 0 243
ENST00000478176 NCOR1P1-001 processed_transcript Homo_sapiens 8.40779e-45 183
ENST00000486162 NCOR1P1-002 transcribed_unprocessed_pseudogene Homo_sapiens 5e-31 137
ENST00000562547 CH17-53B9.2-002 transcribed_unprocessed_pseudogene Homo_sapiens 2e-34 148
ENST00000579606 NCOR1-025 protein_coding Homo_sapiens 0 592
ENST00000579974 NCOR1-021 retained_intron Homo_sapiens 0 195
ENST00000580554 NCOR1-015 protein_coding Homo_sapiens 0 459
ENST00000582357 NCOR1-017 protein_coding Homo_sapiens 0 2300
ENST00000583226 NCOR1-028 processed_transcript Homo_sapiens 0 627
ENST00000583234 NCOR1-014 retained_intron Homo_sapiens 0 351
ENST00000584872 NCOR1-027 retained_intron Homo_sapiens 0 754
ENST00000585296 NCOR1-020 retained_intron Homo_sapiens 0 929
ENST00000618784 CH17-53B9.2-001 processed_transcript Homo_sapiens 0 213

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