C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor corepressor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000141027 NCOR1 9606 - 17:16029157-16218185 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000268712 NCOR1-001 16029157-16215549 protein_coding
  ENST00000395848 NCOR1-007 16091564-16194639 protein_coding
  ENST00000395849 NCOR1-018 16032092-16080007 protein_coding
  ENST00000395851 NCOR1-003 16031404-16194613 protein_coding
  ENST00000395857 NCOR1-201 16030096-16215560 protein_coding
  ENST00000411510 NCOR1-009 16126082-16215537 protein_coding
  ENST00000430577 NCOR1-012 16171863-16218185 protein_coding
  ENST00000436068 NCOR1-006 16086399-16091918 protein_coding
  ENST00000436828 NCOR1-002 16126132-16215530 protein_coding
  ENST00000458113 NCOR1-022 16046900-16080513 retained_intron
  ENST00000460276 NCOR1-008 16126132-16215530 nonsense_mediated_decay
  ENST00000464381 NCOR1-010 16031404-16058336 retained_intron
  ENST00000466825 NCOR1-011 16198171-16215401 processed_transcript
  ENST00000470782 NCOR1-005 16031404-16068412 retained_intron
  ENST00000472189 NCOR1-013 16056974-16057935 retained_intron
  ENST00000579573 NCOR1-026 16032473-16047035 protein_coding
  ENST00000579606 NCOR1-025 16040445-16057730 protein_coding
  ENST00000579974 NCOR1-021 16164906-16194611 retained_intron
  ENST00000580554 NCOR1-015 16039517-16057723 protein_coding
  ENST00000580617 NCOR1-024 16031988-16040108 retained_intron
  ENST00000582357 NCOR1-017 16126107-16215529 protein_coding
  ENST00000582565 NCOR1-023 16032433-16040659 retained_intron
  ENST00000583226 NCOR1-028 16101718-16122635 processed_transcript
  ENST00000583234 NCOR1-014 16046892-16049397 retained_intron
  ENST00000584872 NCOR1-027 16061867-16065885 retained_intron
  ENST00000585296 NCOR1-020 16164871-16215548 retained_intron
  ENST00000603989 NCOR1-029 16039220-16039466 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000268712ENST00000395848ENST00000395849ENST00000395851ENST00000395857ENST00000411510ENST00000464381ENST00000582357
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000268712 N/A 4.651±0.00 2.455±0.00 1.984±0.40 2.028±0.00 6.990±0.00 1.732±0.00 4.098±0.00 3.311±1.76 4.825±0.00 N/A 3.539±1.59 1.132±0.00 N/A
ENST00000395848 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.780±0.00 N/A
ENST00000395849 N/A N/A N/A 5.218±0.00 N/A N/A 5.184±0.00 8.495±0.00 N/A 7.273±0.00 8.288±0.64 12.161±3.79 5.738±0.44 11.581±0.00
ENST00000395851 8.100±0.00 7.982±0.00 2.465±0.00 3.875±1.82 4.214±0.77 6.784±1.48 2.802±1.71 6.744±0.00 4.555±0.00 2.944±0.00 4.566±2.92 10.175±4.39 5.817±2.59 12.131±2.91
ENST00000395857 4.596±0.00 N/A 2.495±0.00 2.749±0.00 2.402±0.00 4.673±0.00 1.675±0.00 2.857±0.16 3.168±0.00 3.626±0.00 3.095±0.00 2.496±0.00 1.108±0.00 4.835±0.00
ENST00000411510 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 15.206±0.00 N/A
ENST00000464381 N/A N/A N/A N/A N/A N/A N/A N/A 7.086±0.00 N/A N/A 9.870±0.00 N/A N/A
ENST00000582357 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 35.477±0.00 N/A 30.382±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000H6 CIL_0000H6_0001 CGP 17:15976560-16045015
CIL_0000NU CIL_0000NU_0001 CGP 17:15999380-16218185
CIL_0006JO CIL_0006JO_0002 CGP 17:16029157-16351797

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000118 IDA histone deacetylase complex
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0002361 IEA CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003714 IMP transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0005737 IEA cytoplasm
GO:0005876 IDA spindle microtubule
GO:0006351 TAS transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007219 TAS Notch signaling pathway
GO:0010467 TAS gene expression
GO:0014067 IEA negative regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 IDA membrane
GO:0016568 IEA chromatin modification
GO:0016580 IDA Sin3 complex
GO:0017053 IDA transcriptional repressor complex
GO:0021794 IEA thalamus development
GO:0031065 IEA positive regulation of histone deacetylation
GO:0032922 IEA circadian regulation of gene expression
GO:0035033 IEA histone deacetylase regulator activity
GO:0035257 IPI nuclear hormone receptor binding
GO:0040014 IEA regulation of multicellular organism growth
GO:0042632 IEA cholesterol homeostasis
GO:0042826 IPI histone deacetylase binding
GO:0042974 IEA retinoic acid receptor binding
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 ISS transcription regulatory region DNA binding
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0046329 IDA negative regulation of JNK cascade
GO:0046965 IEA retinoid X receptor binding
GO:0046966 IEA thyroid hormone receptor binding
GO:0051225 IMP spindle assembly
GO:0060318 IEA definitive erythrocyte differentiation
GO:0072362 IMP regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter
GO:0072368 IMP regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter
GO:2000191 IC regulation of fatty acid transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035285 ncor1 nuclear receptor co-repressor 1 protein_coding Danio_rerio
ENSMUSG00000018501 Ncor1 nuclear receptor co-repressor 1 protein_coding Mus_musculus

Loading