C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: malate dehydrogenase 2, NAD (mitochondrial)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019179 Mdh2 10090 + 5:135778480-135790398 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000019323 Mdh2-001 135778480-135790391 protein_coding
  ENSMUST00000130795 Mdh2-003 135778677-135784614 retained_intron
  ENSMUST00000138101 Mdh2-002 135778662-135790398 nonsense_mediated_decay
  ENSMUST00000143747 Mdh2-004 135778722-135783752 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000019323ENSMUST00000138101
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000019323 106.322±74.84 360.502±47.09 110.411±5.37 94.867±46.22 239.919±116.82 164.793±109.56 336.392±34.14 121.616±32.55 92.467±46.07 102.965±45.08 331.630±130.07 194.732±99.72 127.537±71.14 27.333±12.33
ENSMUST00000138101 N/A N/A N/A 99.158±0.00 42.704±0.00 N/A N/A 54.142±0.00 N/A N/A 85.092±16.96 123.969±22.52 193.761±111.46 7.743±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006NU CIL_0006NU_0002 CGP 5:135747220-135790398
CIL_0006NT CIL_0006NT_0002 CGP 5:135778480-135874772

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0005759 IEA mitochondrial matrix
GO:0005886 IEA plasma membrane
GO:0006099 IEA tricarboxylic acid cycle
GO:0006107 IEA oxaloacetate metabolic process
GO:0006108 ISA malate metabolic process
GO:0006475 ISS internal protein amino acid acetylation
GO:0006734 IEA NADH metabolic process
GO:0016615 ISA malate dehydrogenase activity
GO:0030060 IDA L-malate dehydrogenase activity
GO:0043621 IEA protein self-association
GO:0044262 IEA cellular carbohydrate metabolic process
GO:0044822 IEA poly(A) RNA binding
GO:0046554 IEA malate dehydrogenase (NADP+) activity
GO:0055114 ISA oxidation-reduction process
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043371 mdh2 malate dehydrogenase 2, NAD (mitochondrial) protein_coding Danio_rerio
ENSG00000146701 MDH2 malate dehydrogenase 2, NAD (mitochondrial) protein_coding Homo_sapiens

Loading