C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: growth factor receptor bound protein 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019312 Grb7 10090 + 11:98446394-98455373 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000019456 Grb7-001 98446834-98455373 protein_coding
  ENSMUST00000127914 Grb7-006 98447048-98455373 retained_intron
  ENSMUST00000129034 Grb7-003 98453789-98455125 retained_intron
  ENSMUST00000132771 Grb7-002 98446394-98451417 protein_coding
  ENSMUST00000133419 Grb7-004 98451842-98453822 retained_intron
  ENSMUST00000156328 Grb7-005 98447068-98455373 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000019456ENSMUST00000127914ENSMUST00000129034ENSMUST00000132771ENSMUST00000133419ENSMUST00000156328
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000019456 5.236±3.96 0.452±0.08 12.568±3.83 0.424±0.13 9.334±2.71 47.003±5.41 0.180±0.12 56.833±5.01 38.522±19.49 14.710±1.38 0.072±0.00 3.955±2.14 8.961±7.90 0.739±0.25
ENSMUST00000127914 1.296±0.80 N/A 5.387±1.04 0.059±0.00 2.408±0.36 8.725±1.35 N/A N/A 3.795±1.67 4.126±0.30 0.071±0.00 1.283±0.05 2.529±1.26 0.286±0.06
ENSMUST00000129034 0.521±0.00 N/A N/A N/A 3.612±1.25 N/A 0.145±0.02 N/A N/A N/A 0.117±0.05 2.131±0.02 N/A 0.435±0.00
ENSMUST00000132771 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.145±0.00 N/A N/A N/A
ENSMUST00000133419 N/A 0.374±0.10 N/A N/A N/A N/A 0.133±0.00 N/A N/A N/A 0.135±0.00 N/A N/A N/A
ENSMUST00000156328 N/A N/A 3.208±0.00 N/A N/A N/A 0.047±0.02 N/A N/A N/A 0.053±0.02 1.501±0.00 0.849±0.00 0.178±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008SN CIL_0008SN_0002 VISTA 11:97857859-98458466
CIL_00080Z CIL_00080Z_0002 VISTA 11:98039002-98639485
CIL_00098W CIL_00098W_0002 VISTA 11:98077499-98680383
CIL_0007WH CIL_0007WH_0002 VISTA 11:98091902-98695006
CIL_0002E0 CIL_0002E0_0002 CGP 11:98437708-98455373
CIL_0002PT CIL_0002PT_0002 CGP 11:98446394-98546031

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003723 IEA RNA binding
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005515 IPI protein binding
GO:0005829 TAS:ISS cytosol
GO:0005886 IEA plasma membrane
GO:0005925 ISS focal adhesion
GO:0007165 TAS signal transduction
GO:0009967 TAS positive regulation of signal transduction
GO:0010494 IDA cytoplasmic stress granule
GO:0017148 IMP negative regulation of translation
GO:0019901 IEA protein kinase binding
GO:0030335 ISS positive regulation of cell migration
GO:0034063 IMP stress granule assembly
GO:0035091 ISS phosphatidylinositol binding
GO:0042802 IEA identical protein binding
GO:0042995 IEA cell projection

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042726 GRB7 growth factor receptor-bound protein 7 protein_coding Danio_rerio
ENSG00000141738 GRB7 growth factor receptor-bound protein 7 protein_coding Homo_sapiens

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