C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: regulatory factor X, 4 (influences HLA class II expression)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020037 Rfx4 10090 + 10:84756062-84906538 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020226 Rfx4-001 84838148-84872502 processed_transcript
  ENSMUST00000060397 Rfx4-003 84756062-84906144 protein_coding
  ENSMUST00000095388 Rfx4-002 84838148-84906538 protein_coding
  ENSMUST00000165868 Rfx4-005 84762238-84814670 processed_transcript
  ENSMUST00000166696 Rfx4-006 84834746-84906534 protein_coding
  ENSMUST00000173479 Rfx4-004 84762238-84814670 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020226ENSMUST00000060397ENSMUST00000095388ENSMUST00000166696
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020226 0.044±0.02 N/A 0.014±0.00 N/A 0.090±0.00 N/A N/A 0.038±0.00 0.017±0.02 N/A N/A 0.118±0.08 N/A N/A
ENSMUST00000060397 N/A N/A N/A 5.677±3.42 N/A N/A N/A 0.058±0.02 N/A N/A 0.001±0.00 N/A N/A 3.339±0.00
ENSMUST00000095388 0.011±0.00 0.041±0.02 0.007±0.00 2.044±0.76 0.048±0.02 0.021±0.00 0.016±0.01 0.163±0.09 2.161±1.67 0.061±0.03 0.006±0.00 0.057±0.03 0.014±0.00 19.339±7.85
ENSMUST00000166696 N/A 0.003±0.00 N/A 0.717±0.00 N/A N/A N/A 0.090±0.08 N/A N/A N/A N/A N/A 4.751±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00028K CIL_00028K_0002 CGP 10:84622437-84906538
CIL_0007NZ CIL_0007NZ_0002 UCNEbase 10:84657795-84823112
CIL_0001MF CIL_0001MF_0002 CGP 10:84756062-85016446

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0021516 IMP dorsal spinal cord development
GO:0021537 IMP telencephalon development
GO:0021696 IMP cerebellar cortex morphogenesis
GO:0021914 IMP negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0030900 IMP forebrain development
GO:0030901 IMP midbrain development
GO:0042384 IMP cilium assembly
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0070613 IMP regulation of protein processing

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026395 rfx4 regulatory factor X, 4 protein_coding Danio_rerio
ENSG00000111783 RFX4 regulatory factor X, 4 (influences HLA class II expression) protein_coding Homo_sapiens

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