C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: regulatory factor X, 4 (influences HLA class II expression)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000111783 RFX4 9606 + 12:106582907-106762803 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000229387 RFX4-001 106684696-106762803 protein_coding
  ENST00000357881 RFX4-003 106601137-106761659 protein_coding
  ENST00000392842 RFX4-002 106582907-106762802 protein_coding
  ENST00000536688 RFX4-006 106601172-106733506 retained_intron
  ENST00000536722 RFX4-005 106601166-106715527 nonsense_mediated_decay
  ENST00000539967 RFX4-004 106585727-106715544 protein_coding
  ENST00000546882 RFX4-008 106583033-106682054 nonsense_mediated_decay
  ENST00000549040 RFX4-009 106583645-106686932 protein_coding
  ENST00000551640 RFX4-010 106645882-106709430 protein_coding
  ENST00000552773 RFX4-007 106639332-106683466 retained_intron
  ENST00000552866 RFX4-011 106684696-106693159 protein_coding
  ENST00000552917 RFX4-012 106684808-106709389 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastHeartKidneyLiverOvaryTestisENST00000229387ENST00000357881ENST00000392842ENST00000536688ENST00000551640
Transcript ID Adipose Adrenal Brain Breast Heart Kidney Liver Ovary Testis
ENST00000229387 0.034±0.00 N/A 5.425±0.00 0.011±0.00 N/A 0.042±0.00 N/A 0.003±0.00 63.790±40.32
ENST00000357881 N/A N/A N/A N/A 0.024±0.00 N/A N/A N/A N/A
ENST00000392842 N/A N/A 4.694±3.82 N/A N/A N/A N/A N/A N/A
ENST00000536688 N/A 0.128±0.00 N/A 0.015±0.00 0.013±0.00 0.037±0.00 0.039±0.00 0.015±0.00 N/A
ENST00000551640 N/A N/A 1.602±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00028K CIL_00028K_0001 CGP 12:106357658-106762803
CIL_0007NZ CIL_0007NZ_0001 UCNEbase 12:106418267-106672625
CIL_0001MF CIL_0001MF_0001 CGP 12:106582907-106889316

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0021516 IEA dorsal spinal cord development
GO:0021537 IEA telencephalon development
GO:0021696 IEA cerebellar cortex morphogenesis
GO:0021914 IEA negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning
GO:0030900 IEA forebrain development
GO:0030901 IEA midbrain development
GO:0042384 IEA cilium assembly
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0070613 IEA regulation of protein processing

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000026395 rfx4 regulatory factor X, 4 protein_coding Danio_rerio
ENSMUSG00000020037 Rfx4 regulatory factor X, 4 (influences HLA class II expression) protein_coding Mus_musculus

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