C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020456 Ogdh 10090 + 11:6291633-6356642 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000003461 Ogdh-001 6291633-6356642 protein_coding
  ENSMUST00000081894 Ogdh-003 6292605-6356592 protein_coding
  ENSMUST00000093350 Ogdh-002 6291668-6356592 protein_coding
  ENSMUST00000101554 Ogdh-004 6291666-6356578 protein_coding
  ENSMUST00000125929 Ogdh-008 6291641-6297677 retained_intron
  ENSMUST00000135124 Ogdh-006 6292172-6313818 protein_coding
  ENSMUST00000140765 Ogdh-005 6291985-6313934 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003461ENSMUST00000081894ENSMUST00000093350ENSMUST00000101554
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003461 64.555±24.51 42.547±20.40 51.500±8.83 21.904±10.45 41.067±17.92 37.537±11.77 260.763±10.44 105.476±5.68 26.273±5.81 46.147±4.31 174.393±9.74 43.434±15.75 43.498±11.31 9.532±1.75
ENSMUST00000081894 N/A N/A N/A 3.588±0.00 N/A 29.101±8.92 N/A N/A 9.841±3.13 N/A N/A N/A 10.688±5.99 11.384±1.34
ENSMUST00000093350 N/A N/A N/A 9.372±7.35 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000101554 27.089±11.57 131.242±18.80 N/A N/A 67.230±24.00 27.451±12.05 196.825±42.56 57.972±13.31 16.367±3.34 33.511±5.38 N/A 22.934±10.79 N/A 3.810±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000J7 CIL_0000J7_0002 CGP 11:6270369-6356642
CIL_0000J8 CIL_0000J8_0002 CGP 11:6291633-6406158

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004591 IEA:ISS oxoglutarate dehydrogenase (succinyl-transferring) activity
GO:0005739 IDA mitochondrion
GO:0006091 ISS generation of precursor metabolites and energy
GO:0006096 IEA glycolytic process
GO:0006099 IEA tricarboxylic acid cycle
GO:0006103 IEA 2-oxoglutarate metabolic process
GO:0006104 IEA succinyl-CoA metabolic process
GO:0006734 IEA NADH metabolic process
GO:0021695 IEP cerebellar cortex development
GO:0021756 IEP striatum development
GO:0021766 IEP hippocampus development
GO:0021794 IEP thalamus development
GO:0021860 IEP pyramidal neuron development
GO:0022028 IEP tangential migration from the subventricular zone to the olfactory bulb
GO:0030976 IEA thiamine pyrophosphate binding
GO:0031072 IEA heat shock protein binding
GO:0031966 ISS mitochondrial membrane
GO:0034602 IDA oxoglutarate dehydrogenase (NAD+) activity
GO:0045252 IEA oxoglutarate dehydrogenase complex
GO:0046872 IEA metal ion binding
GO:0051087 IEA chaperone binding
GO:0061034 IEP olfactory bulb mitral cell layer development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034270 ogdha oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide) protein_coding Danio_rerio
ENSDARG00000073805 ogdhb oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide) protein_coding Danio_rerio
ENSG00000105953 OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) protein_coding Homo_sapiens

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