C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrin beta 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020689 Itgb3 10090 + 11:104608000-104670476 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021028 Itgb3-001 104608000-104670476 protein_coding
  ENSMUST00000127140 Itgb3-002 104637389-104669813 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021028ENSMUST00000127140
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021028 8.190±6.14 2.886±0.27 28.986±4.43 0.344±0.22 6.456±1.72 6.915±0.74 1.253±0.14 0.442±0.17 5.859±5.16 8.081±1.18 0.147±0.04 22.538±8.21 30.047±15.49 0.272±0.16
ENSMUST00000127140 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.220±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HD CIL_0008HD_0002 VISTA 11:104342398-104943585
CIL_0004WN CIL_0004WN_0002 CGP 11:104550663-104670476
CIL_0006XZ CIL_0006XZ_0002 CGP 11:104608000-104753962

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004872 IEA receptor activity
GO:0005178 IPI integrin binding
GO:0005515 IPI protein binding
GO:0005634 ISO nucleus
GO:0007044 IDA cell-substrate junction assembly
GO:0007160 IGI cell-matrix adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0009897 IDA external side of plasma membrane
GO:0016324 IDA apical plasma membrane
GO:0030334 IMP regulation of cell migration
GO:0030335 IMP positive regulation of cell migration
GO:0033690 IMP positive regulation of osteoblast proliferation
GO:0034679 TAS integrin alpha9-beta1 complex
GO:0043235 ISO receptor complex
GO:0045672 IC positive regulation of osteoclast differentiation
GO:0045780 IC positive regulation of bone resorption
GO:0048858 IC cell projection morphogenesis
GO:0060055 IEA angiogenesis involved in wound healing
GO:0070527 IEA platelet aggregation
GO:0071133 IDA alpha9-beta1 integrin-ADAM8 complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045070 itgb3b integrin beta 3b protein_coding Danio_rerio
ENSDARG00000056767 itgb3a integrin beta 3a protein_coding Danio_rerio
ENSG00000259207 ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) protein_coding Homo_sapiens
ENSG00000259753 ITGB3 Integrin beta {ECO:0000256|RuleBase:RU000633} protein_coding Homo_sapiens

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