C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin beta 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000021028 Itgb3-001 ENSMUSG00000020689 10090 + 11:104608000-104670476 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021028
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021028 8.190±6.14 2.886±0.27 28.986±4.43 0.344±0.22 6.456±1.72 6.915±0.74 1.253±0.14 0.442±0.17 5.859±5.16 8.081±1.18 0.147±0.04 22.538±8.21 30.047±15.49 0.272±0.16

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HD CIL_0008HD_0002 VISTA 11:104342398-104943585
CIL_0004WN CIL_0004WN_0002 CGP 11:104550663-104670476
CIL_0006XZ CIL_0006XZ_0002 CGP 11:104608000-104753962

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004872 IEA receptor activity
GO:0005178 IPI integrin binding
GO:0005515 IPI protein binding
GO:0005634 ISO nucleus
GO:0007044 IDA cell-substrate junction assembly
GO:0007160 IGI cell-matrix adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0009897 IDA external side of plasma membrane
GO:0016324 IDA apical plasma membrane
GO:0030334 IMP regulation of cell migration
GO:0030335 IMP positive regulation of cell migration
GO:0033690 IMP positive regulation of osteoblast proliferation
GO:0034679 TAS integrin alpha9-beta1 complex
GO:0043235 ISO receptor complex
GO:0045672 IC positive regulation of osteoclast differentiation
GO:0045780 IC positive regulation of bone resorption
GO:0048858 IC cell projection morphogenesis
GO:0060055 IEA angiogenesis involved in wound healing
GO:0070527 IEA platelet aggregation
GO:0071133 IDA alpha9-beta1 integrin-ADAM8 complex

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000559488 ITGB3-001 protein_coding Homo_sapiens 0 2907
ENST00000560629 ITGB3-001 nonsense_mediated_decay Homo_sapiens 0 2532
ENST00000571680 ITGB3-004 protein_coding Homo_sapiens 0 1417

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