C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protease (prosome, macropain) 26S subunit, ATPase 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020708 Psmc5 10090 + 11:106256154-106263120 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021049 Psmc5-001 106256154-106263120 protein_coding
  ENSMUST00000133131 Psmc5-002 106256154-106263120 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021049ENSMUST00000133131
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021049 31.521±5.59 10.286±3.45 72.590±4.45 115.746±54.28 22.695±3.56 20.206±2.63 32.014±0.89 36.034±2.70 58.955±38.52 28.844±4.28 73.229±2.78 36.584±27.36 97.312±43.20 62.223±19.06
ENSMUST00000133131 N/A N/A N/A N/A 3.488±0.00 N/A N/A N/A N/A N/A N/A 5.390±2.77 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009B9 CIL_0009B9_0002 VISTA 11:105834084-106435839
CIL_0006Q9 CIL_0006Q9_0002 CGP 11:106249142-106263120
CIL_0006QA CIL_0006QA_0002 CGP 11:106256154-106272972

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000502 ISS proteasome complex
GO:0005102 IPI receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISS nucleus
GO:0005675 ISA holo TFIIH complex
GO:0005737 ISS cytoplasm
GO:0005838 IDA proteasome regulatory particle
GO:0006200 IEA ATP catabolic process
GO:0006508 IEA proteolysis
GO:0008134 ISS transcription factor binding
GO:0008233 IEA peptidase activity
GO:0016020 IEA membrane
GO:0016234 IEA inclusion body
GO:0017025 IEA TBP-class protein binding
GO:0022624 IDA proteasome accessory complex
GO:0030163 IEA protein catabolic process
GO:0031410 IEA cytoplasmic vesicle
GO:0031531 ISS thyrotropin-releasing hormone receptor binding
GO:0031595 IEA nuclear proteasome complex
GO:0031597 IEA cytosolic proteasome complex
GO:0043161 ISS proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0070062 IEA extracellular vesicular exosome
GO:0072562 IEA blood microparticle
GO:0090261 IEA positive regulation of inclusion body assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015315 psmc5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 protein_coding Danio_rerio
ENSG00000087191 PSMC5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 protein_coding Homo_sapiens

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