C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, ionotropic, NMDA2C (epsilon 3)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020734 Grin2c 10090 - 11:115249169-115267243 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000003351 Grin2c-001 115249169-115265429 protein_coding
  ENSMUST00000106554 Grin2c-201 115249169-115267243 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003351ENSMUST00000106554
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003351 0.019±0.01 2.878±0.55 0.124±0.06 0.342±0.00 0.103±0.07 0.019±0.01 0.444±0.05 0.113±0.04 0.056±0.03 0.602±0.04 0.022±0.01 1.828±0.45 0.120±0.08 N/A
ENSMUST00000106554 0.035±0.00 2.629±1.69 N/A 5.600±0.00 0.071±0.01 N/A 0.113±0.01 0.074±0.02 0.026±0.01 1.195±0.00 N/A 1.546±0.63 0.058±0.00 0.088±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000286 CIL_000286_0002 CGP 11:115187487-115267243
CIL_0001FN CIL_0001FN_0002 CGP 11:115249169-115277050

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004972 IGI N-methyl-D-aspartate selective glutamate receptor activity
GO:0005234 IBA extracellular-glutamate-gated ion channel activity
GO:0005261 IMP cation channel activity
GO:0005515 IPI protein binding
GO:0006812 IMP cation transport
GO:0008104 IGI protein localization
GO:0009611 IGI response to wounding
GO:0014069 IDA postsynaptic density
GO:0017146 IPI N-methyl-D-aspartate selective glutamate receptor complex
GO:0030054 IEA cell junction
GO:0030165 IEA PDZ domain binding
GO:0030425 IBA dendrite
GO:0033058 IGI directional locomotion
GO:0034220 IBA ion transmembrane transport
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0042177 IGI negative regulation of protein catabolic process
GO:0042391 IMP regulation of membrane potential
GO:0045211 IBA postsynaptic membrane
GO:0047485 IEA protein N-terminus binding
GO:0050885 IMP neuromuscular process controlling balance
GO:0060079 IMP regulation of excitatory postsynaptic membrane potential
GO:0098655 IMP cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077560 grin2cb glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb protein_coding Danio_rerio
ENSDARG00000078149 grin2ca glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca protein_coding Danio_rerio
ENSG00000161509 GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C protein_coding Homo_sapiens

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