C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate receptor, ionotropic, NMDA2C (epsilon 3)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000003351 Grin2c-001 ENSMUSG00000020734 10090 - 11:115249169-115265429 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000003351
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000003351 0.019±0.01 2.878±0.55 0.124±0.06 0.342±0.00 0.103±0.07 0.019±0.01 0.444±0.05 0.113±0.04 0.056±0.03 0.602±0.04 0.022±0.01 1.828±0.45 0.120±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000286 CIL_000286_0002 CGP 11:115187487-115267243
CIL_0001FN CIL_0001FN_0002 CGP 11:115249169-115277050

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004972 IGI N-methyl-D-aspartate selective glutamate receptor activity
GO:0005234 IBA extracellular-glutamate-gated ion channel activity
GO:0005261 IMP cation channel activity
GO:0005515 IPI protein binding
GO:0006812 IMP cation transport
GO:0008104 IGI protein localization
GO:0009611 IGI response to wounding
GO:0014069 IDA postsynaptic density
GO:0017146 IPI N-methyl-D-aspartate selective glutamate receptor complex
GO:0030054 IEA cell junction
GO:0030425 IBA dendrite
GO:0033058 IGI directional locomotion
GO:0034220 IBA ion transmembrane transport
GO:0035249 IBA synaptic transmission, glutamatergic
GO:0042177 IGI negative regulation of protein catabolic process
GO:0042391 IMP regulation of membrane potential
GO:0045211 IBA postsynaptic membrane
GO:0050885 IMP neuromuscular process controlling balance
GO:0060079 IMP regulation of excitatory postsynaptic membrane potential
GO:0098655 IMP cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000263269 GRIN2D-001 protein_coding Homo_sapiens 0 994
ENST00000293190 GRIN2C-001 protein_coding Homo_sapiens 0 4026
ENST00000330684 GRIN2A-002 protein_coding Homo_sapiens 0 649
ENST00000347612 GRIN2C-002 protein_coding Homo_sapiens 0 3243
ENST00000396573 GRIN2A-001 protein_coding Homo_sapiens 0 649
ENST00000396575 GRIN2A-201 protein_coding Homo_sapiens 0 649
ENST00000463531 GRIN2A-003 processed_transcript Homo_sapiens 4e-34 148
ENST00000535259 GRIN2A-202 protein_coding Homo_sapiens 0 649
ENST00000562109 GRIN2A-006 protein_coding Homo_sapiens 0 649
ENST00000578159 GRIN2C-005 processed_transcript Homo_sapiens 0 641
ENST00000584176 GRIN2C-004 retained_intron Homo_sapiens 0 1138

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